Hub : Traits : Bone surface : ←

chr10:95,263,631-96,660,473

Trait: Bone surface

Best TWAS P=2.059084e-07 · Best GWAS P=1.807484e-07 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Brain	Kcnj16	gene expression	ENSRNOG00000004713	0.25	0.42	lasso	41	0.43	3.2e-43	5.0	5.2	2.1e-07	0.11	0.50	0.50	TRUE
2	Brain	Kcnj16	isoform ratio	ENSRNOT00000095753	0.06	0.09	lasso	4	0.09	2.1e-08	5.2	-5.1	2.9e-07	-0.94	0.42	0.58	TRUE
3	PL	Kcnj16	gene expression	ENSRNOG00000004713	0.03	0.01	blup	2691	0.01	2.9e-02	5.0	5.1	3.5e-07	0.97	0.44	0.48	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.