Hub : Traits : dissection: UMAP 1 of all traits : ← →

chr3:91,159,360-93,417,804

Best TWAS P=1.190221e-08 · Best GWAS P=2.089535e-08 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	AABR07053185.1	gene expression	ENSRNOG00000004787	0.04	0.03	top1	1	0.03	2.3e-04	5.2	5.2	2.2e-07	0.99	0.06	0.05	FALSE
2	Adipose	AABR07053185.1	isoform ratio	ENSRNOT00000006385	0.28	0.31	blup	966	0.31	4.4e-35	5.2	5.2	1.7e-07	1.00	0.46	0.54	FALSE
3	Adipose	AABR07053185.1	isoform ratio	ENSRNOT00000097695	0.28	0.31	blup	966	0.31	5.9e-35	5.2	-5.2	1.7e-07	-1.00	0.46	0.54	FALSE
4	Adipose	AABR07053185.1	intron excision ratio	chr3:92302780:92314624	0.34	0.34	enet	205	0.34	1.6e-39	5.2	-5.5	4.0e-08	-0.99	0.44	0.56	FALSE
5	Adipose	AABR07053185.1	intron excision ratio	chr3:92302783:92314624	0.34	0.34	enet	204	0.35	5.2e-40	5.2	5.5	3.8e-08	0.99	0.44	0.56	FALSE
6	Adipose	AABR07053185.1	mRNA stability	ENSRNOG00000004787	0.08	0.06	blup	966	0.07	5.8e-08	4.2	5.1	3.2e-07	0.98	0.52	0.48	FALSE
7	BLA	Dcdc5	alternative TSS	ENSRNOT00000115631	0.06	0.03	blup	1381	0.05	1.3e-03	5.4	-5.3	1.4e-07	-1.00	0.54	0.42	FALSE
8	BLA	AABR07053185.1	gene expression	ENSRNOG00000004787	0.06	0.03	top1	1	0.03	6.8e-03	5.6	5.6	2.4e-08	1.00	0.04	0.05	FALSE
9	BLA	AABR07053185.1	isoform ratio	ENSRNOT00000006385	0.30	0.40	blup	967	0.41	9.3e-24	5.1	5.3	1.5e-07	1.00	0.43	0.57	FALSE
10	BLA	AABR07053185.1	isoform ratio	ENSRNOT00000097695	0.30	0.40	blup	967	0.41	1.8e-23	5.1	-5.3	1.5e-07	-1.00	0.44	0.56	FALSE
11	BLA	AABR07053185.1	intron excision ratio	chr3:92302780:92314624	0.47	0.50	blup	967	0.51	3.4e-31	5.1	-5.1	3.3e-07	-0.99	0.50	0.50	FALSE
12	BLA	AABR07053185.1	intron excision ratio	chr3:92302783:92314624	0.47	0.50	blup	967	0.51	2.1e-31	5.1	5.1	3.0e-07	0.99	0.50	0.50	FALSE
13	BLA	AABR07053185.1	mRNA stability	ENSRNOG00000004787	0.12	0.12	top1	1	0.12	4.6e-07	5.2	5.2	2.3e-07	0.99	0.58	0.34	FALSE
14	Brain	Pax6	gene expression	ENSRNOG00000004410	0.16	0.10	lasso	53	0.10	2.9e-09	5.4	5.3	1.5e-07	1.00	0.23	0.77	FALSE
15	Brain	AABR07053185.1	gene expression	ENSRNOG00000004787	0.04	0.05	top1	1	0.05	4.2e-05	5.2	5.2	2.3e-07	0.99	0.13	0.09	FALSE
16	Brain	AABR07053185.1	intron excision ratio	chr3:92302780:92314624	0.63	0.56	blup	967	0.57	1.1e-63	5.1	-5.3	1.4e-07	-1.00	0.43	0.57	FALSE
17	Brain	AABR07053185.1	intron excision ratio	chr3:92302783:92314624	0.63	0.56	blup	967	0.57	9.8e-64	5.1	5.3	1.4e-07	1.00	0.43	0.57	FALSE
18	Brain	AABR07053185.1	mRNA stability	ENSRNOG00000004787	0.16	0.20	lasso	98	0.20	4.8e-18	5.1	5.1	3.1e-07	1.00	0.44	0.56	FALSE
19	Eye	AABR07053185.1	isoform ratio	ENSRNOT00000097695	0.56	0.12	blup	967	0.20	5.2e-04	5.1	-5.3	1.0e-07	-0.96	0.33	0.45	FALSE
20	Eye	AABR07053185.1	intron excision ratio	chr3:92302780:92314624	0.35	0.11	top1	1	0.11	8.6e-03	5.4	-5.4	5.7e-08	-0.99	0.06	0.06	FALSE
21	Eye	AABR07053185.1	intron excision ratio	chr3:92302783:92314624	0.38	0.11	top1	1	0.11	9.1e-03	5.4	5.4	5.7e-08	0.99	0.06	0.06	FALSE
22	IL	AABR07053185.1	isoform ratio	ENSRNOT00000006385	0.31	0.22	blup	963	0.25	1.1e-06	5.2	5.3	1.3e-07	1.00	0.44	0.55	FALSE
23	IL	AABR07053185.1	isoform ratio	ENSRNOT00000097695	0.30	0.21	blup	963	0.24	1.4e-06	5.1	-5.3	1.3e-07	-1.00	0.44	0.55	FALSE
24	IL	AABR07053185.1	intron excision ratio	chr3:92302780:92314624	0.57	0.33	blup	963	0.36	2.0e-09	5.2	-5.3	9.6e-08	-1.00	0.43	0.57	FALSE
25	IL	AABR07053185.1	intron excision ratio	chr3:92302783:92314624	0.57	0.32	blup	963	0.34	4.0e-09	5.2	5.3	9.2e-08	1.00	0.43	0.57	FALSE
26	IL	AABR07053185.1	mRNA stability	ENSRNOG00000004787	0.22	0.14	blup	963	0.15	2.2e-04	5.1	5.1	2.9e-07	0.99	0.45	0.47	FALSE
27	LHb	AABR07053185.1	isoform ratio	ENSRNOT00000006385	0.28	0.21	blup	961	0.22	5.8e-06	5.4	5.2	2.3e-07	0.99	0.46	0.52	FALSE
28	LHb	AABR07053185.1	isoform ratio	ENSRNOT00000097695	0.28	0.18	blup	961	0.22	6.2e-06	5.4	-5.2	2.3e-07	-0.99	0.46	0.52	FALSE
29	LHb	AABR07053185.1	intron excision ratio	chr3:92302780:92314624	0.45	0.26	enet	20	0.30	5.6e-08	5.3	-5.2	1.6e-07	-0.99	0.48	0.52	FALSE
30	LHb	AABR07053185.1	intron excision ratio	chr3:92302783:92314624	0.45	0.27	enet	22	0.31	3.9e-08	5.2	5.2	2.3e-07	1.00	0.48	0.52	FALSE
31	Liver	AABR07053185.1	gene expression	ENSRNOG00000004787	0.13	0.10	blup	966	0.11	9.7e-12	5.5	5.2	2.6e-07	0.99	0.48	0.52	FALSE
32	Liver	Rcn1	gene expression	ENSRNOG00000013452	0.04	0.03	top1	1	0.03	6.8e-04	5.2	-5.2	2.5e-07	-0.88	0.04	0.17	FALSE
33	Liver	AABR07053185.1	isoform ratio	ENSRNOT00000006385	0.24	0.21	blup	966	0.22	5.7e-24	5.2	5.1	2.7e-07	0.99	0.48	0.52	FALSE
34	Liver	AABR07053185.1	isoform ratio	ENSRNOT00000097695	0.25	0.22	blup	966	0.22	2.0e-24	5.2	-5.1	2.7e-07	-0.99	0.48	0.52	FALSE
35	Liver	AABR07053185.1	intron excision ratio	chr3:92302780:92314624	0.45	0.27	enet	246	0.28	2.3e-31	5.4	-5.7	1.2e-08	-0.98	0.40	0.60	TRUE
36	Liver	AABR07053185.1	intron excision ratio	chr3:92302783:92314624	0.45	0.27	enet	232	0.28	2.3e-31	5.4	5.7	1.3e-08	0.98	0.40	0.60	FALSE
37	NAcc	AABR07053185.1	isoform ratio	ENSRNOT00000006385	0.32	0.24	enet	6	0.25	3.1e-06	5.2	5.2	1.6e-07	0.99	0.43	0.56	FALSE
38	NAcc	AABR07053185.1	isoform ratio	ENSRNOT00000097695	0.33	0.24	enet	9	0.25	2.4e-06	5.2	-5.2	1.7e-07	-0.92	0.43	0.56	FALSE
39	NAcc	AABR07053185.1	intron excision ratio	chr3:92302780:92314624	0.46	0.44	top1	1	0.44	5.4e-11	5.4	-5.4	6.9e-08	-0.99	0.32	0.60	FALSE
40	NAcc	AABR07053185.1	intron excision ratio	chr3:92302783:92314624	0.46	0.44	top1	1	0.44	2.9e-11	5.4	5.4	6.9e-08	0.99	0.33	0.61	FALSE
41	NAcc	AABR07053185.1	mRNA stability	ENSRNOG00000004787	0.26	0.15	top1	1	0.15	3.5e-04	5.5	5.5	3.6e-08	0.99	0.06	0.09	FALSE
42	NAcc2	AABR07053185.1	intron excision ratio	chr3:92302780:92314624	0.46	0.46	lasso	44	0.47	2.5e-28	5.1	-5.1	3.0e-07	-0.99	0.46	0.54	FALSE
43	NAcc2	AABR07053185.1	intron excision ratio	chr3:92302783:92314624	0.43	0.46	lasso	49	0.47	2.9e-28	5.1	5.1	2.7e-07	0.99	0.46	0.54	FALSE
44	NAcc2	Dnajc24	intron excision ratio	chr3:92455243:92485048	0.04	0.01	blup	1147	0.02	1.8e-02	5.4	5.3	9.8e-08	1.00	0.39	0.40	FALSE
45	OFC	AABR07053185.1	isoform ratio	ENSRNOT00000006385	0.47	0.10	top1	1	0.10	2.2e-03	5.4	5.4	6.9e-08	0.99	0.06	0.06	FALSE
46	OFC	AABR07053185.1	isoform ratio	ENSRNOT00000097695	0.49	0.10	top1	1	0.10	2.1e-03	5.4	-5.4	6.9e-08	-0.99	0.06	0.06	FALSE
47	OFC	AABR07053185.1	intron excision ratio	chr3:92302780:92314624	0.21	0.12	blup	963	0.13	5.6e-04	5.4	-5.2	1.6e-07	-1.00	0.42	0.49	FALSE
48	OFC	AABR07053185.1	intron excision ratio	chr3:92302783:92314624	0.22	0.13	blup	963	0.14	4.2e-04	5.4	5.2	1.7e-07	1.00	0.42	0.50	FALSE
49	OFC	AABR07053185.1	mRNA stability	ENSRNOG00000004787	0.29	0.25	top1	1	0.25	1.2e-06	5.4	5.4	6.2e-08	0.99	0.10	0.15	FALSE
50	PL	AABR07053185.1	isoform ratio	ENSRNOT00000006385	0.34	0.30	lasso	4	0.31	4.8e-08	5.4	5.3	1.2e-07	1.00	0.46	0.54	FALSE
51	PL	AABR07053185.1	isoform ratio	ENSRNOT00000097695	0.34	0.30	lasso	4	0.30	9.4e-08	5.1	-5.2	1.9e-07	-1.00	0.47	0.53	FALSE
52	PL2	AABR07053185.1	gene expression	ENSRNOG00000004787	0.06	0.03	blup	967	0.05	1.4e-03	4.8	5.1	3.2e-07	0.98	0.42	0.47	FALSE
53	PL2	AABR07053185.1	isoform ratio	ENSRNOT00000006385	0.31	0.36	lasso	83	0.37	8.2e-21	5.4	5.4	7.2e-08	1.00	0.39	0.61	FALSE
54	PL2	AABR07053185.1	isoform ratio	ENSRNOT00000097695	0.31	0.36	lasso	61	0.36	1.1e-20	5.4	-5.4	7.4e-08	-1.00	0.39	0.61	FALSE
55	PL2	AABR07053185.1	intron excision ratio	chr3:92302780:92314624	0.47	0.42	top1	1	0.42	9.3e-25	5.4	-5.4	5.8e-08	-0.99	0.31	0.69	FALSE
56	PL2	AABR07053185.1	intron excision ratio	chr3:92302783:92314624	0.46	0.42	lasso	49	0.42	1.3e-24	5.4	5.4	7.0e-08	1.00	0.38	0.62	FALSE
57	PL2	AABR07053185.1	mRNA stability	ENSRNOG00000004787	0.23	0.24	top1	1	0.24	2.9e-13	5.1	5.1	3.3e-07	0.99	0.71	0.29	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.