Best TWAS P=2.286372e-07 · Best GWAS P=0.005278624 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PL | Epha6 | alternative TSS | ENSRNOT00000047310 | 0.03 | 0.03 | enet | 548 | 0.03 | 0.0034 | -1.8 | -5.2 | 2.3e-07 | 0.97 | 0.23 | 0.15 | TRUE |
| 2 | PL | Epha6 | alternative TSS | ENSRNOT00000097751 | 0.04 | 0.03 | enet | 379 | 0.03 | 0.0012 | -1.8 | 5.2 | 2.5e-07 | -0.97 | 0.24 | 0.16 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.