Best TWAS P=1.641826e-07 · Best GWAS P=3.859057e-05 conditioned to 0.01020502
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Cspg4 | mRNA stability | ENSRNOG00000017208 | 0.18 | 0.04 | enet | 52 | 0.05 | 6.8e-06 | -3.9 | -5.2 | 1.6e-07 | 0.32 | 0.41 | 0.56 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.