Best TWAS P=3.436137e-07 · Best GWAS P=8.04323e-06 conditioned to 0.4816921
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NAcc | Aamdc | alternative polyA | ENSRNOT00000113509 | 0.2 | 0.06 | enet | 77 | 0.12 | 3.6e-09 | -3.8 | 5.1 | 3.4e-07 | 0.79 | 0.51 | 0.48 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.