Best TWAS P=4.506231e-08 · Best GWAS P=3.718478e-05 conditioned to 0.4517883
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Eye | Ttc39c | intron excision ratio | chr18:3853105:3855503 | 0.38 | 0.1 | enet | 52 | 0.18 | 0.0011 | 3.9 | 5.5 | 4.5e-08 | 0.65 | 0.35 | 0.26 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.