Best TWAS P=1.241643e-10 · Best GWAS P=0.004081541 conditioned to 5.57276e-11
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Liver | Ccs | gene expression | ENSRNOG00000047816 | 0.07 | 0.05 | enet | 10 | 0.06 | 5.1e-07 | 0.58 | -6.4 | 1.2e-10 | -0.46 | 0.05 | 0.03 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.