Best TWAS P=4.893806e-08 · Best GWAS P=6.232929e-06 conditioned to 0.1326572
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | BLA | Arhgdig | gene expression | ENSRNOG00000068707 | 0.11 | 0.06 | enet | 155 | 0.08 | 3.8e-05 | -4 | -5.5 | 4.9e-08 | 0.61 | 0.49 | 0.5 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.