Best TWAS P=2.209761e-07 · Best GWAS P=3.188333e-05 conditioned to 0.1221621
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | Efhd1 | mRNA stability | ENSRNOG00000015596 | 0.5 | 0.18 | enet | 190 | 0.2 | 2.7e-22 | 3.9 | -5.2 | 2.2e-07 | -0.55 | 0.22 | 0.76 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.