Best TWAS P=5.809727e-13 · Best GWAS P=1.16584e-05 conditioned to 0.006691335
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NAcc | Ccdc57 | alternative TSS | ENSRNOT00000095877 | 0.27 | 0.02 | blup | 1793 | 0.02 | 0.0059 | -3.4 | 7.2 | 5.8e-13 | 0.24 | 0.25 | 0.12 | TRUE |
| 2 | NAcc | Ccdc57 | alternative TSS | ENSRNOT00000098223 | 0.24 | 0.02 | blup | 1793 | 0.02 | 0.0077 | -3.4 | -7.1 | 9.2e-13 | -0.24 | 0.25 | 0.13 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.