Best TWAS P=2.972824e-10 · Best GWAS P=0.05301975 conditioned to 4.055727e-16
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Eral1 | gene expression | ENSRNOG00000010673 | 0.04 | 0.01 | enet | 183 | 0.02 | 0.00088 | -1.7 | 6.3 | 3e-10 | 0.66 | 0.07 | 0.07 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.