Best TWAS P=5.532548e-08 · Best GWAS P=0.06923396 conditioned to 0.0008357945
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PL | Tmem11 | gene expression | ENSRNOG00000005377 | 0.17 | 0.08 | enet | 12 | 0.11 | 0.0017 | -1.2 | -5.4 | 5.5e-08 | 0.74 | 0.02 | 0.02 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.