Best TWAS P=2.920303e-12 · Best GWAS P=0.03996311 conditioned to 5.737198e-19
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | Eral1 | gene expression | ENSRNOG00000010673 | 0.04 | 0.01 | enet | 183 | 0.02 | 0.00088 | 1.8 | -7 | 2.9e-12 | 0.66 | 0.08 | 0.08 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.