Best TWAS P=1.283755e-07 · Best GWAS P=1.184876e-06 conditioned to 1
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | BLA | Ilrun | gene expression | ENSRNOG00000038883 | 0.86 | 0.43 | blup | 2269 | 0.56 | 3.9e-35 | -4.5 | 5.3 | 1.3e-07 | -0.93 | 0.13 | 0.87 | TRUE |
2 | OFC | Ilrun | gene expression | ENSRNOG00000038883 | 0.90 | 0.22 | enet | 209 | 0.52 | 1.5e-14 | -4.5 | 5.1 | 2.9e-07 | -0.98 | 0.13 | 0.86 | FALSE |
3 | PL2 | Ilrun | gene expression | ENSRNOG00000038883 | 0.86 | 0.45 | lasso | 75 | 0.56 | 2.8e-36 | -4.9 | 5.2 | 2.1e-07 | -0.89 | 0.12 | 0.88 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.