Best TWAS P=4.807649e-12 · Best GWAS P=0.0453127 conditioned to 7.254595e-25
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Liver | Stk40 | mRNA stability | ENSRNOG00000025679 | 0.26 | 0.04 | blup | 1102 | 0.13 | 2e-14 | -1 | -6.9 | 4.8e-12 | -0.91 | 0.05 | 0.03 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.