Best TWAS P=4.90832e-08 · Best GWAS P=1.656216e-06 conditioned to 0.131017
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Liver | Il6st | gene expression | ENSRNOG00000013963 | 0.12 | 0.02 | enet | 151 | 0.04 | 2.9e-05 | 3.4 | 5.5 | 4.9e-08 | -0.67 | 0.82 | 0.11 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.