Best TWAS P=7.604882e-08 · Best GWAS P=0.02081187 conditioned to 1.011112e-13
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | Glt8d1 | gene expression | ENSRNOG00000018179 | 0.54 | 0.02 | blup | 1227 | 0.07 | 1.3e-08 | 0.85 | -5.4 | 7.6e-08 | 0.64 | 0.02 | 0.01 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.