Best TWAS P=4.154522e-24 · Best GWAS P=0.00348809 conditioned to 0.002521162
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | BLA | Syt5 | mRNA stability | ENSRNOG00000018217 | 0.06 | 0 | enet | 782 | 0.01 | 0.16 | -0.38 | -10 | 4.2e-24 | 0.54 | 0.18 | 0.03 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.