Best TWAS P=2.407104e-07 · Best GWAS P=3.838445e-07 conditioned to 0.2565769
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NAcc2 | Tmem117 | gene expression | ENSRNOG00000006068 | 0.38 | 0.08 | blup | 2498 | 0.16 | 6.7e-09 | -4.5 | -5.2 | 2.4e-07 | 0.88 | 0.64 | 0.35 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.