Best TWAS P=3.060468e-07 · Best GWAS P=4.33601e-06 conditioned to 0.9875549
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | Wscd1 | gene expression | ENSRNOG00000007869 | 0.37 | 0.41 | enet | 66 | 0.43 | 2.5e-51 | 4.3 | 5.1 | 3.1e-07 | 0.9 | 0.42 | 0.57 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.