Best TWAS P=6.695221e-08 · Best GWAS P=0.009946031 conditioned to 0.081505
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Liver | Rnasel | gene expression | ENSRNOG00000027017 | 0.05 | 0 | blup | 1178 | 0.01 | 0.02 | -2.2 | 5.4 | 6.7e-08 | -0.71 | 0.03 | 0.04 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.