Best TWAS P=6.707831e-08 · Best GWAS P=4.711838e-07 conditioned to 0.09369126
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PL | Pnpla8 | gene expression | ENSRNOG00000039091 | 0.34 | 0.05 | blup | 2582 | 0.18 | 5.5e-05 | -3.5 | -5.4 | 6.7e-08 | -0.72 | 0.41 | 0.49 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.