Best TWAS P=2.241203e-07 · Best GWAS P=2.492033e-05 conditioned to 0.0602577
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | Cep295nl | gene expression | ENSRNOG00000033143 | 0.25 | 0.12 | enet | 194 | 0.22 | 6.9e-24 | -1.9 | 5.2 | 2.2e-07 | 0.5 | 0.88 | 0.05 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.