Hub : Traits

Short access day 1 locomotion

Tags: Behavior · Cocaine · Short access

Project: p50_paul_meyer_2020

4 loci · 4 genes with independent associations · 4 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr4	176059677	177381574	1	1	1.26e-07	1.28e-01	3.90e-09	Slco1a1
2	chr7	92127461	93066096	1	1	9.85e-13	5.60e-01	1.00e+00	Ndufb9
3	chr9	83390749	84777604	1	1	0.00e+00	5.45e-02	1.00e+00	Retreg2
4	chr20	43987022	45386226	1	1	7.04e-08	5.06e-01	1.07e-08	LOC134483824

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	294.21	3	2	50	0	1.00e+00	Ndufb9 Retreg2 Slco1a1
BMI without tail	28629.5	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Body weight	6.83	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Slco1a1
Epididymis fat weight	18141.5	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Glucose	273.97	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Heart weight	1536.76	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Left kidney weight	27527.72	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Right kidney weight	20206.48	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Tail length	14460.46	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Length with tail	746.74	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Length without tail	15747.8	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Slco1a1
Liver weight, left	1747.19	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Liver weight, right	19.71	3	1	25	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Parametrial fat weight	95.21	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Retroperitoneal fat weight	3938.69	1	1	25	0	1.00e+00	Retreg2
Intraocular pressure	5195.51	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Extensor digitorum longus weight	1077.67	1	1	25	0	1.00e+00	Retreg2
Soleus weight	9.27	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Slco1a1
Tibialis anterior weight	1158.38	1	1	25	0	1.00e+00	Retreg2
Tibia length	385.43	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Number of licking bursts	33715.41	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Food consumed during 24 hour testing period	35509.41	1	1	25	0	1.00e+00	Retreg2
Times rat made contact with spout	32.13	3	1	25	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Mean time between licks in bursts	55817.09	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Mean num. licks in bursts	56750.08	1	1	25	0	1.00e+00	Retreg2
Std. dev. time between licks in bursts	29750.31	1	1	25	0	1.00e+00	Retreg2
Water consumed over 24 hours	34168.6	1	1	25	0	1.00e+00	Retreg2
Patch foraging indifference point 0 sec	39171.5	1	1	25	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	25072.33	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Indifference point function ln k	27852.12	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Indifference point function log k	27852.12	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Patch foraging total patch changes 0 sec	41947.04	1	1	25	0	1.00e+00	Retreg2
Patch foraging total patch changes 12 sec	785.14	3	2	50	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Patch foraging total patch changes 18 sec	20233.2	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Patch foraging total patch changes 24 sec	24966.81	3	2	50	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Patch foraging total patch changes 6 sec	3903.01	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Patch foraging time to switch 0 sec	33254.99	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 0 sec	30219.01	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 12 sec	70639.93	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 18 sec	16866.98	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 24 sec	1033.47	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 6 sec	435.09	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Locomotor activity	4.13	1	0	0	0	1.00e+00	Ndufb9
Locomotor testing distance	9226.37	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Slco1a1
Locomotor testing rearing	21135.22	3	1	25	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Light reinforcement 1	66311.75	1	1	25	0	1.00e+00	Retreg2
Light reinforcement 2	18371.56	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Reaction time number correct	21164.63	3	2	50	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Reaction time mean minus median	59977.3	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Reaction time mean minus median AUC	62002.11	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Reaction time num false alarms	7684.56	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Reaction time num false alarms AUC	17512.77	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Reaction time trials correct on left	21164.63	3	2	50	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Reaction time trials on left	20301.36	3	2	50	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Reaction time mean	29724.21	1	1	25	0	1.00e+00	Retreg2
Reaction time mean AUC	38768	1	1	25	0	1.00e+00	Retreg2
Median of all reaction times	7893.84	1	1	25	0	1.00e+00	Retreg2
Reaction time omissions	2793.89	3	1	25	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Reaction time false alarm rate	77.47	3	1	25	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Reaction time premature initiation rate	9733.76	1	1	25	0	1.00e+00	Retreg2
Reaction time premature initiations	53743.58	1	1	25	0	1.00e+00	Retreg2
Std. dev. reaction times	30435.18	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Reaction time trials completed	20301.36	3	2	50	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Reaction time trials AUC	20715.98	3	1	25	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Social response proportion	8777.03	1	1	25	0	1.00e+00	Retreg2
Social responses	635.8	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Social time	11650.06	1	1	25	0	1.00e+00	Retreg2
Conditioned locomotion	1400.08	1	1	25	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	19128.47	1	1	25	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	18571.31	1	1	25	0	1.00e+00	Retreg2
Cocaine response before conditioning	655.41	1	1	25	0	1.00e+00	Retreg2
Saline control response	3160.68	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	14521.56	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	14360.59	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active responses	2302.04	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	10889.7	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. lever presses	1935.17	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. lever reinforcers received	469.54	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	2531.81	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	13282.18	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	19909.31	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. index score	12744.53	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	16150.81	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	5331.08	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	4012.39	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	34989.79	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	11800.43	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	1164.95	1	1	25	0	1.00e+00	Retreg2
Conditioned reinforcement - actives	50420.83	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Conditioned reinforcement - inactives	32455.53	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Conditioned locomotion	3472.78	3	2	50	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Intermittent access intake day 1-15 change	127876.18	1	1	25	0	1.00e+00	Retreg2
Intermittent access intake escalation	126068.82	1	1	25	0	1.00e+00	Retreg2
Intermittent access intake escalation 2	36175.43	1	1	25	0	1.00e+00	Retreg2
Intermitt. access day 1 inactive lever presses	90309.52	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Intermitt. access day 15 inactive lever presses	41247.31	3	2	50	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Intermitt. access escalation Index	46653.32	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Intermittent access day 1 total infusions	33061.72	2	1	25	0	1.00e+00	Retreg2 Slco1a1
Intermittent access day 15 total infusions	48731.91	1	1	25	0	1.00e+00	Retreg2
Intermittent access terminal intake (last 3 days)	12402.82	2	1	25	0	1.00e+00	Retreg2 Slco1a1
Intermittent access total infusions	94.57	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Intermittent access day 1 locomotion	17488.03	2	1	25	0	1.00e+00	Retreg2 Slco1a1
Intermittent access day 15 total locomotion	85548.8	1	1	25	0	1.00e+00	Retreg2
Intermittent access total locomotion	64.05	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Intermittent access standard deviation	56985.4	2	1	25	0	1.00e+00	Retreg2 Slco1a1
Cocaine induced anxiety	34589.88	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Post-drug Anxiety	2390.18	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Baseline Anxiety	16852.64	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Lifetime Intake	832.41	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Incentive Sensitization - Responses	35692.61	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Incentive Sensitization - Breakpoint	27649.77	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio test 1 active lever presses	8005.33	4	1	25	1	6.68e-05	LOC134483824 Ndufb9 Retreg2 Slco1a1
Progressive ratio test 1 breakpoint	7585.24	4	1	25	1	4.40e-05	LOC134483824 Ndufb9 Retreg2 Slco1a1
Progressive ratio test 1 inactive lever presses	15566.92	4	3	75	1	5.32e-05	LOC134483824 Ndufb9 Retreg2 Slco1a1
Progressive ratio test 2 active lever presses	7635.38	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio test 2 breakpoint	4274.2	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio test 2 inactive lever presses	24172.03	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Slco1a1
Total sessions with >9 infusions	661.66	3	1	25	0	1.00e+00	LOC134483824 Retreg2 Slco1a1
Short access day 1 total inactive lever presses	13148.34	3	2	50	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Short access day 10 total inactive lever presses	138842.31	1	1	25	0	1.00e+00	Retreg2
Short access day 1 total infusions	12807.7	3	2	50	0	1.00e+00	LOC134483824 Retreg2 Slco1a1
Short access day 10 total infusions	7577.28	3	2	50	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Short access total infusions	4398.31	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Short access day 10 total locomotion	44090.94	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Short access total locomotion	4675.2	4	1	25	1	3.56e-05	LOC134483824 Ndufb9 Retreg2 Slco1a1
Compulsive drug intake	6235.01	3	1	25	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
One hour access (0.3 mA shock)	786.43	3	2	50	0	1.00e+00	Ndufb9 Retreg2 Slco1a1
One hour access (shock baseline)	18333.75	3	1	25	0	1.00e+00	LOC134483824 Retreg2 Slco1a1
Number of responses in last shaping day	4544.19	3	1	25	0	1.00e+00	LOC134483824 Retreg2 Slco1a1
Context. condit. distance diff. score	212.47	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 1	1769.63	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Locomotion distance, session 1	1024.77	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 2	2158.08	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 2	508.11	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 3	507.49	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 3	4009.46	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	1361.96	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	2872.44	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 7	150.94	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Locomotion distance, session 7	292.53	3	1	25	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Stereotopy head waving bouts, day 7	1279.33	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving duration, day 7	1081.37	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Locomotion velocity, session 8	409.23	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 8	147.88	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization distance	3670.85	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	1029.63	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active minus inactive responses	482.09	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Condit. Reinf. active-inactive response ratio	242.03	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active responses	2765.7	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	2347.53	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Incentive salience index mean	1773.78	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Condit. Reinf. lever presses	2643.66	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Time in familiar zone, hab. session 1	11168.49	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	9232.79	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, hab. session 1	149.35	3	1	25	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Total locomotion distance, hab. session 1	394.1	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 1	266.96	1	1	25	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	5880.03	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	6311.49	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	35.66	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 2	22.17	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 2	31.27	1	1	25	0	1.00e+00	Retreg2
Novel to familiar place preference ratio	15339.58	1	1	25	0	1.00e+00	Retreg2
Novelty place preference	14927.56	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, NPP test	10685.62	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, NPP test	980.79	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, NPP test	1687.31	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, NPP test	953.07	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	248.61	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. change in total contacts	1037.76	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. index score	384.43	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	404.63	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	344.19	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. magazine entry number	491.61	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	69.21	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	418.89	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	583.93	1	1	25	0	1.00e+00	Retreg2
Bone: apparent density	2735.95	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone surface	6197.68	1	1	25	0	1.00e+00	Retreg2
Bone volume	8624.75	1	1	25	0	1.00e+00	Retreg2
Bone: connectivity density	841.82	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical apparent density	4017.15	3	2	50	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Bone: cortical area	2293.91	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical porosity	150.69	3	1	25	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Bone: cortical porosity	376.17	3	1	25	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Bone: cortical thickness	128.8	3	1	25	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Bone: cortical thickness	1464.97	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical tissue density	4344.57	3	2	50	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Bone: elastic displacement	7604.03	1	1	25	0	1.00e+00	Retreg2
Bone: elastic work	361.86	1	1	25	0	1.00e+00	Retreg2
Bone: endosteal estimation	4460.13	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone: endosteal perimeter	11863.6	1	1	25	0	1.00e+00	Retreg2
Bone: final force	1600.36	1	1	25	0	1.00e+00	Retreg2
Bone: final moment	219.15	1	1	25	0	1.00e+00	Retreg2
Bone: marrow area	4718.77	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum diameter	3037.24	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum force	8697.09	1	1	25	0	1.00e+00	Retreg2
Bone: maximum moment	2996.54	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone: minimum diameter	2053.27	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Bone: periosteal estimation	9791.57	1	1	25	0	1.00e+00	Retreg2
Bone: periosteal perimeter	5702.1	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Bone: post-yield work	13672.98	1	1	25	0	1.00e+00	Retreg2
Bone: stiffness	9032.86	1	1	25	0	1.00e+00	Retreg2
Bone: tissue strength	2995.95	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular number	5387.39	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular spacing	3988.39	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular thickness	8476.26	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular tissue density	7288.68	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Breakpoint value in progressive ratio session	18814.8	2	2	50	0	1.00e+00	LOC134483824 Retreg2
Distance traveled before self-admin	25271.77	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Distance traveled after self-admin	32464.08	1	1	25	0	1.00e+00	Retreg2
Delta time in closed arm before/after self-admin	86.93	3	1	25	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Delta time in open arm before/after self-admin	15131.21	1	1	25	0	1.00e+00	Retreg2
Diff in mean of infusions in LGA sessions	18328.29	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Extinction: sum of active levers before priming	9476.91	3	2	50	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Active lever presses in extinction session 6	372.98	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Delta distance traveled before/after self-admin	1485.64	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Delta ambulatory time before/after self-admin	15429.45	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Time in closed arm before self-admin	8960.51	3	1	25	0	1.00e+00	LOC134483824 Retreg2 Slco1a1
Time in closed arm after self-admin	4591.18	1	1	25	0	1.00e+00	Retreg2
Time in open arm before self-admin	4407.84	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Time in open arm after self-admin	261.21	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Sum of active levers in priming session hrs 5-6	496.26	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Time to tail flick, vehicle, before self-admin	4462.64	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Slco1a1
Time to tail flick, vehicle, after self-admin	21081.01	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Time to tail flick, test, before self-admin	4093.6	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Time to tail flick, test, after self-admin	739.72	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Delta time to tail flick, vehicle, before/after SA	4910.95	2	1	25	0	1.00e+00	Retreg2 Slco1a1
Delta time to tail flick, test, before/after SA	7848.65	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Ambulatory time before self-admin	78874.38	1	1	25	0	1.00e+00	Retreg2
Ambulatory time after self-admin	26614.91	1	1	25	0	1.00e+00	Retreg2
Total heroin consumption	127.58	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Area under the delay curve	24791.27	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 0s delay	1083.28	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Delay disc. indifference point, 16s delay	21959.9	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 2s delay	155.27	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 24s delay	32437.06	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 4s delay	315.77	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Delay disc. indifference point, 8s delay	33362.4	1	1	25	0	1.00e+00	Retreg2
Delay discount exponential model param	16922.54	1	1	25	0	1.00e+00	Retreg2
Delay discount hyperbolic model param	12277.65	1	1	25	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	61202.36	1	1	25	0	1.00e+00	Retreg2
Change in fecal boli incidents, locomotor task	2849.45	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Time >=10cm from walls, locomotor time 1	4341.72	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Slco1a1
Bouts of movement, locomotor time 1	5395.51	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Total resting periods, locomotor time 1	2793.59	1	1	25	0	1.00e+00	Retreg2
Rest time, locomotor task time 1	11183.83	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Distance moved, locomotor task time 1	34443.92	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Vertical activity count, locomotor time 1	142354.07	1	1	25	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	71159.6	1	1	25	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 2	82029.05	1	1	25	0	1.00e+00	Retreg2
Total resting periods, locomotor time 2	99042.67	1	1	25	0	1.00e+00	Retreg2
Rest time, locomotor task time 2	12756.26	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Distance moved, locomotor task time 2	4241.68	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Vertical activity count, locomotor time 2	53555.35	1	1	25	0	1.00e+00	Retreg2
Weight adjusted by age	35416.78	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Seeking ratio, delayed vs. immediate footshock	13445.31	1	1	25	0	1.00e+00	Retreg2
Locomotion in novel chamber	1993.33	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Locomotion in novel chamber post-restriction	32715.18	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio	22646.88	3	2	50	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Food seeking constrained by brief footshock	941.83	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Seeking ratio, punishment vs. effort	20653.58	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Run reversals in cocaine runway, females	9406.04	1	1	25	0	1.00e+00	Retreg2
Run reversals in cocaine runway, males	3884.61	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Latency to leave start box in cocaine runway	16290.75	1	1	25	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, F	3596.44	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Latency to leave start box in cocaine runway, M	867.32	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Cd content in liver	8.89	1	0	0	0	1.00e+00	LOC134483824
Co content in liver	573.41	2	1	25	0	1.00e+00	LOC134483824 Retreg2
Cu content in liver	28.08	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Fe content in liver	675.94	2	1	25	0	1.00e+00	LOC134483824 Retreg2
K content in liver	1519.62	1	1	25	0	1.00e+00	Retreg2
Mg content in liver	6026.97	1	1	25	0	1.00e+00	Retreg2
Mn content in liver	537.3	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Na content in liver	2013.84	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Rb content in liver	71.08	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Se content in liver	8.63	1	0	0	0	1.00e+00	Ndufb9
Sr content in liver	8.05	1	0	0	0	1.00e+00	LOC134483824
Zn content in liver	1261.42	3	2	50	0	1.00e+00	LOC134483824 Ndufb9 Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.08
Adipose	alternative TSS	0	0	1.15
Adipose	gene expression	1	0	1.16
Adipose	isoform ratio	0	0	1.11
Adipose	intron excision ratio	0	0	1.09
Adipose	mRNA stability	1	0	1.17
BLA	alternative polyA	0	0	1.06
BLA	alternative TSS	0	0	1.13
BLA	gene expression	0	0	1.13
BLA	isoform ratio	0	0	1.07
BLA	intron excision ratio	0	0	1.05
BLA	mRNA stability	0	0	1.12
Brain	alternative polyA	0	0	1.1
Brain	alternative TSS	0	0	1.09
Brain	gene expression	0	0	1.15
Brain	isoform ratio	0	0	1.11
Brain	intron excision ratio	0	0	1.03
Brain	mRNA stability	0	0	1.14
Eye	alternative polyA	0	0	0.97
Eye	alternative TSS	0	0	1.02
Eye	gene expression	0	0	1.19
Eye	isoform ratio	0	0	1.19
Eye	intron excision ratio	0	0	1.06
Eye	mRNA stability	0	0	1.07
IC	alternative polyA	0	0	1.07
IC	alternative TSS	0	0	1.19
IC	gene expression	0	0	1.16
IC	isoform ratio	0	0	1.11
IC	intron excision ratio	0	0	1.06
IC	mRNA stability	0	0	1.14
IL	alternative polyA	0	0	1.12
IL	alternative TSS	0	0	1.16
IL	gene expression	0	0	1.11
IL	isoform ratio	0	0	1.1
IL	intron excision ratio	0	0	1.03
IL	mRNA stability	0	0	1.18
LHb	alternative polyA	0	0	1.13
LHb	alternative TSS	0	0	1.2
LHb	gene expression	0	0	1.09
LHb	isoform ratio	0	0	1.13
LHb	intron excision ratio	0	0	1.02
LHb	mRNA stability	0	0	1.19
Liver	alternative polyA	0	0	1.11
Liver	alternative TSS	0	0	1.1
Liver	gene expression	0	0	1.15
Liver	isoform ratio	0	0	1.13
Liver	intron excision ratio	0	0	1.02
Liver	mRNA stability	1	0	1.16
NAcc	alternative polyA	1	0	9.92
NAcc	alternative TSS	0	0	1.16
NAcc	gene expression	0	0	1.14
NAcc	isoform ratio	0	0	1.16
NAcc	intron excision ratio	0	0	1.11
NAcc	mRNA stability	0	0	1.16
OFC	alternative polyA	0	0	1.13
OFC	alternative TSS	0	0	1.14
OFC	gene expression	0	0	1.12
OFC	isoform ratio	0	0	1.06
OFC	intron excision ratio	0	0	1
OFC	mRNA stability	0	0	1.12
PL	alternative polyA	0	0	1.17
PL	alternative TSS	0	0	1.15
PL	gene expression	0	0	1.16
PL	isoform ratio	0	0	1.13
PL	intron excision ratio	0	0	1.11
PL	mRNA stability	0	0	1.17
pVTA	alternative polyA	0	0	1.14
pVTA	alternative TSS	0	0	1.19
pVTA	gene expression	0	0	1.15
pVTA	isoform ratio	0	0	1.13
pVTA	intron excision ratio	0	0	1.06
pVTA	mRNA stability	0	0	1.16
RMTg	alternative polyA	0	0	0.98
RMTg	alternative TSS	0	0	1.09
RMTg	gene expression	0	0	1.15
RMTg	isoform ratio	0	0	1.1
RMTg	intron excision ratio	0	0	1.05
RMTg	mRNA stability	0	0	1.13