Short access day 1 total inactive lever presses

Tags: Behavior · Cocaine · Short access

Project: p50_paul_meyer_2020

5 loci · 5 genes with independent associations · 5 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr1	88613126	89913275	1	1	4.94e-08	1.09e-01	1.93e-03	Zfp575
2	chr2	144511896	145907690	1	1	8.53e-08	2.22e-01	1.00e+00	Mindy4b
3	chr7	92127461	93066096	1	1	2.15e-10	3.03e-01	1.00e+00	Ndufb9
4	chr8	117463629	118343328	1	1	3.25e-28	2.69e-01	1.00e+00	Mst1
5	chr9	83390749	84777604	1	1	0.00e+00	3.05e-01	1.00e+00	Retreg2

Pleiotropic Associations

Trait	Chi² ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	Corr	Corr P	Genes
BMI with tail	296.8	3	3	60	0	1.00e+00	Mindy4b Ndufb9 Retreg2
BMI without tail	19088.19	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Body weight	8.36	4	3	60	-0.34	6.58e-01	Mindy4b Mst1 Ndufb9 Retreg2
Epididymis fat weight	12102.23	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Glucose	226.07	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Heart weight	1536.76	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Left kidney weight	18352.75	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Right kidney weight	13476.76	3	3	60	0	1.00e+00	Mst1 Ndufb9 Retreg2
Tail length	14460.63	2	1	20	0	1.00e+00	Mst1 Retreg2
Length with tail	501.6	3	3	60	0	1.00e+00	Mst1 Ndufb9 Retreg2
Length without tail	9452.58	5	2	40	1	7.69e-05	Mindy4b Mst1 Ndufb9 Retreg2 Zfp575
Liver weight, left	1172.72	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Liver weight, right	24.67	4	2	40	0.66	3.39e-01	Mindy4b Mst1 Ndufb9 Retreg2
Parametrial fat weight	181.56	1	1	20	0	1.00e+00	Retreg2
Retroperitoneal fat weight	1324.54	3	2	40	0	1.00e+00	Mindy4b Mst1 Retreg2
Intraocular pressure	10386.52	1	1	20	0	1.00e+00	Retreg2
Extensor digitorum longus weight	361.65	3	1	20	0	1.00e+00	Mindy4b Mst1 Retreg2
Soleus weight	9.26	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Tibialis anterior weight	580.28	2	1	20	0	1.00e+00	Mst1 Retreg2
Tibia length	265.42	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Number of licking bursts	67424.86	1	1	20	0	1.00e+00	Retreg2
Food consumed during 24 hour testing period	17761.06	2	1	20	0	1.00e+00	Mst1 Retreg2
Times rat made contact with spout	41.61	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Mean time between licks in bursts	55817.09	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Mean num. licks in bursts	56750.08	1	1	20	0	1.00e+00	Retreg2
Std. dev. time between licks in bursts	14881.26	2	1	20	0	1.00e+00	Mst1 Retreg2
Water consumed over 24 hours	17087.8	2	1	20	0	1.00e+00	Mst1 Retreg2
Patch foraging indifference point 0 sec	19591.07	2	1	20	0	1.00e+00	Mst1 Retreg2
Patch foraging indifference point AUC	16748.54	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Indifference point function ln k	18623.38	3	3	60	0	1.00e+00	Mst1 Ndufb9 Retreg2
Indifference point function log k	18623.38	3	3	60	0	1.00e+00	Mst1 Ndufb9 Retreg2
Patch foraging total patch changes 0 sec	20977.37	2	1	20	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 12 sec	804.18	3	3	60	0	1.00e+00	Mst1 Ndufb9 Retreg2
Patch foraging total patch changes 18 sec	13495.16	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Patch foraging total patch changes 24 sec	18737.11	4	3	60	-1	3.70e-03	Mindy4b Mst1 Ndufb9 Retreg2
Patch foraging total patch changes 6 sec	1954.14	4	2	40	-0.99	5.06e-03	Mindy4b Mst1 Ndufb9 Retreg2
Patch foraging time to switch 0 sec	22171.85	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Patch foraging water rate 0 sec	30219.01	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 12 sec	35322.91	2	1	20	0	1.00e+00	Mst1 Retreg2
Patch foraging water rate 18 sec	11246.65	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Patch foraging water rate 24 sec	523.92	2	1	20	0	1.00e+00	Mst1 Retreg2
Patch foraging water rate 6 sec	291.61	3	2	40	0	1.00e+00	Ndufb9 Retreg2 Zfp575
Locomotor activity	26.79	1	1	20	0	1.00e+00	Mst1
Locomotor testing distance	9234.88	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Locomotor testing rearing	15859.67	4	2	40	1	3.48e-03	Mindy4b Mst1 Ndufb9 Retreg2
Light reinforcement 1	22106.77	3	1	20	0	1.00e+00	Mindy4b Mst1 Retreg2
Light reinforcement 2	9201.6	4	2	40	1	6.44e-04	Mindy4b Mst1 Ndufb9 Retreg2
Reaction time number correct	31744.5	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Reaction time mean minus median	39986.09	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Reaction time mean minus median AUC	41341.25	3	3	60	0	1.00e+00	Mst1 Ndufb9 Retreg2
Reaction time num false alarms	7685.9	2	1	20	0	1.00e+00	Mst1 Retreg2
Reaction time num false alarms AUC	17513.8	2	1	20	0	1.00e+00	Mst1 Retreg2
Reaction time trials correct on left	31744.5	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Reaction time trials on left	30449.82	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Reaction time mean	14876.61	2	2	40	0	1.00e+00	Mindy4b Retreg2
Reaction time mean AUC	19397.23	2	2	40	0	1.00e+00	Mindy4b Retreg2
Median of all reaction times	3966.33	2	2	40	0	1.00e+00	Mindy4b Retreg2
Reaction time omissions	2098.22	4	1	20	-1	1.94e-04	Mindy4b Mst1 Ndufb9 Retreg2
Reaction time false alarm rate	76.38	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Reaction time premature initiation rate	4871.37	2	1	20	0	1.00e+00	Mindy4b Retreg2
Reaction time premature initiations	26874.85	2	1	20	0	1.00e+00	Mindy4b Retreg2
Std. dev. reaction times	15222.04	4	1	20	-1	2.63e-03	Mindy4b Mst1 Ndufb9 Retreg2
Reaction time trials completed	30449.82	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Reaction time trials AUC	31071.82	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Social response proportion	2935.9	3	1	20	0	1.00e+00	Mindy4b Mst1 Retreg2
Social responses	428.93	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Social time	5828.31	2	1	20	0	1.00e+00	Mst1 Retreg2
Conditioned locomotion	1400.08	1	1	20	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	19128.47	1	1	20	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	18571.31	1	1	20	0	1.00e+00	Retreg2
Cocaine response before conditioning	655.41	1	1	20	0	1.00e+00	Retreg2
Saline control response	1639.18	2	2	40	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active minus inactive responses	7271.32	2	2	40	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active-inactive response ratio	14360.59	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active responses	1165.18	2	2	40	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. inactive responses	3646.05	3	2	40	0	1.00e+00	Mindy4b Mst1 Retreg2
Condit. Reinf. lever presses	1311.07	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Condit. Reinf. lever reinforcers received	243.91	2	1	20	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever latency	1278.33	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry latency	6738.25	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. change in total contacts	19909.31	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. index score	6407.33	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. latency score	8109.24	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever contacts	2689.72	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry number	2097.69	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries	17558.57	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	5938.34	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. response bias	641.31	2	2	40	0	1.00e+00	Mst1 Retreg2
Conditioned reinforcement - actives	33615.25	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Conditioned reinforcement - inactives	21684.99	3	3	60	0	1.00e+00	Mst1 Ndufb9 Retreg2
Conditioned locomotion	2611.15	4	3	60	-0.99	8.03e-03	Mindy4b Mst1 Ndufb9 Retreg2
Intermittent access intake day 1-15 change	42634.91	3	2	40	0	1.00e+00	Mindy4b Mst1 Retreg2
Intermittent access intake escalation	42032.13	3	3	60	0	1.00e+00	Mindy4b Mst1 Retreg2
Intermittent access intake escalation 2	12063.19	3	1	20	0	1.00e+00	Mindy4b Mst1 Retreg2
Intermitt. access day 1 inactive lever presses	60230.5	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Intermitt. access day 15 inactive lever presses	61868.22	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Intermitt. access escalation Index	23356.66	4	2	40	1	4.08e-03	Mindy4b Mst1 Ndufb9 Retreg2
Intermittent access day 1 total infusions	22045.49	3	1	20	0	1.00e+00	Mindy4b Mst1 Retreg2
Intermittent access day 15 total infusions	24371.34	2	1	20	0	1.00e+00	Retreg2 Zfp575
Intermittent access terminal intake (last 3 days)	12404.64	2	1	20	0	1.00e+00	Retreg2 Zfp575
Intermittent access total infusions	97.41	2	1	20	0	1.00e+00	Retreg2 Zfp575
Intermittent access day 1 locomotion	17488.68	2	1	20	0	1.00e+00	Mindy4b Retreg2
Intermittent access day 15 total locomotion	85548.8	1	1	20	0	1.00e+00	Retreg2
Intermittent access total locomotion	31.92	5	1	20	-0.83	8.08e-02	Mindy4b Mst1 Ndufb9 Retreg2 Zfp575
Intermittent access standard deviation	56995.61	2	2	40	0	1.00e+00	Mst1 Retreg2
Cocaine induced anxiety	23061.5	3	2	40	0	1.00e+00	Ndufb9 Retreg2 Zfp575
Post-drug Anxiety	1199.73	4	2	40	1	4.66e-03	Mst1 Ndufb9 Retreg2 Zfp575
Baseline Anxiety	11237.13	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Lifetime Intake	833.15	2	1	20	0	1.00e+00	Retreg2 Zfp575
Incentive Sensitization - Responses	17856.7	4	4	80	1	7.96e-04	Mindy4b Ndufb9 Retreg2 Zfp575
Incentive Sensitization - Breakpoint	13836.73	4	4	80	1	8.01e-04	Mindy4b Ndufb9 Retreg2 Zfp575
Progressive ratio test 1 active lever presses	15996.07	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio test 1 breakpoint	15154.62	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio test 1 inactive lever presses	20756.82	3	3	60	0	1.00e+00	Mst1 Ndufb9 Retreg2
Progressive ratio test 2 active lever presses	3822.79	4	1	20	1	7.84e-04	Mindy4b Ndufb9 Retreg2 Zfp575
Progressive ratio test 2 breakpoint	2143.39	4	1	20	1	1.22e-03	Mindy4b Ndufb9 Retreg2 Zfp575
Progressive ratio test 2 inactive lever presses	24171.65	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Total sessions with >9 infusions	510.33	4	2	40	1	2.25e-03	Mindy4b Mst1 Retreg2 Zfp575
Short access day 10 total inactive lever presses	69453.48	2	2	40	0	1.00e+00	Mst1 Retreg2
Short access day 1 total infusions	12800.55	3	1	20	0	1.00e+00	Mst1 Retreg2 Zfp575
Short access day 10 total infusions	5690.54	4	3	60	1	9.28e-04	Mindy4b Mst1 Ndufb9 Retreg2
Short access total infusions	4396.25	2	1	20	0	1.00e+00	Mindy4b Retreg2
Short access day 1 locomotion	6214.96	4	2	40	-0.99	6.91e-03	Mst1 Ndufb9 Retreg2 Zfp575
Short access day 10 total locomotion	29409.12	3	2	40	0	1.00e+00	Mindy4b Mst1 Retreg2
Short access total locomotion	4685.97	4	3	60	-0.99	6.43e-03	Mindy4b Mst1 Ndufb9 Retreg2
Compulsive drug intake	3744.32	5	1	20	0.99	6.01e-04	Mindy4b Mst1 Ndufb9 Retreg2 Zfp575
One hour access (0.3 mA shock)	594.44	4	2	40	-0.99	1.44e-02	Mindy4b Ndufb9 Retreg2 Zfp575
One hour access (shock baseline)	27501.24	2	1	20	0	1.00e+00	Retreg2 Zfp575
Number of responses in last shaping day	3413.22	4	1	20	-0.99	6.34e-03	Mindy4b Mst1 Retreg2 Zfp575
Context. condit. distance diff. score	212.47	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 1	1769.63	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Locomotion distance, session 1	1024.77	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 2	742.23	3	2	40	0	1.00e+00	Mindy4b Mst1 Retreg2
Locomotion distance, session 2	258.11	2	1	20	0	1.00e+00	Mst1 Retreg2
Locomotion velocity, session 3	507.49	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 3	4009.46	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	691.91	2	1	20	0	1.00e+00	Mst1 Retreg2
Stereotopy head waving duration, day 3	1446.08	2	1	20	0	1.00e+00	Mst1 Retreg2
Locomotion velocity, session 7	210.64	2	2	40	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 7	342.68	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Stereotopy head waving bouts, day 7	1279.33	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving duration, day 7	1081.37	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Locomotion velocity, session 8	409.23	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 8	147.88	1	1	20	0	1.00e+00	Retreg2
Degree of sensitization distance	1889.61	2	2	40	0	1.00e+00	Mst1 Retreg2
Degree of sensitization stereotypy	690.43	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Condit. Reinf. active minus inactive responses	484.11	2	1	20	0	1.00e+00	Mindy4b Retreg2
Condit. Reinf. active-inactive response ratio	126.1	2	1	20	0	1.00e+00	Mindy4b Retreg2
Condit. Reinf. active responses	1386.69	2	1	20	0	1.00e+00	Mindy4b Retreg2
Condit. Reinf. inactive responses	1569.87	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Incentive salience index mean	1780.77	2	1	20	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. lever presses	2666.81	2	2	40	0	1.00e+00	Mst1 Retreg2
Time in familiar zone, hab. session 1	5593.23	2	1	20	0	1.00e+00	Mst1 Retreg2
Time in novel zone, hab. session 1	4629.95	2	2	40	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 1	221.7	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 1	394.1	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 1	266.96	1	1	20	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	2966.16	2	2	40	0	1.00e+00	Mst1 Retreg2
Time in novel zone, hab. session 2	3208.33	2	2	40	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 2	28.15	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Total locomotion distance, hab. session 2	14.23	2	1	20	0	1.00e+00	Mst1 Retreg2
Locomotion velocity, hab. session 2	31.27	1	1	20	0	1.00e+00	Retreg2
Novel to familiar place preference ratio	7678.6	2	1	20	0	1.00e+00	Mst1 Retreg2
Novelty place preference	7474.7	2	1	20	0	1.00e+00	Mst1 Retreg2
Time in novel zone, NPP test	5350.34	2	1	20	0	1.00e+00	Mst1 Retreg2
Total zone transitions, NPP test	980.79	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, NPP test	1687.31	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, NPP test	953.07	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	186.46	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Pavlov. Cond. change in total contacts	522.83	2	1	20	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. index score	214.07	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. latency score	224.45	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever contacts	252.4	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Pavlov. Cond. magazine entry number	250.94	2	1	20	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries	60.1	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	223.77	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. response bias	303.26	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: apparent density	2735.95	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone surface	3109.3	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone volume	4317.38	2	1	20	0	1.00e+00	Mst1 Retreg2
Bone: connectivity density	564.06	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: cortical apparent density	6014.36	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical area	1559.21	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: cortical porosity	150.35	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: cortical porosity	560.57	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical thickness	119.21	4	2	40	0.88	1.20e-01	Mindy4b Mst1 Ndufb9 Retreg2
Bone: cortical thickness	996.09	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: cortical tissue density	4339.01	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: elastic displacement	7604.03	1	1	20	0	1.00e+00	Retreg2
Bone: elastic work	195.81	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: endosteal estimation	2232.29	4	1	20	-1	2.57e-03	Mindy4b Mst1 Ndufb9 Retreg2
Bone: endosteal perimeter	5936.33	2	1	20	0	1.00e+00	Mst1 Retreg2
Bone: final force	840.18	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: final moment	146.88	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: marrow area	3148.45	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: maximum diameter	2046.98	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: maximum force	4390.32	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: maximum moment	2024.32	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: minimum diameter	2061.38	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: periosteal estimation	4919.52	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: periosteal perimeter	5722.93	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: post-yield work	4563.91	3	1	20	0	1.00e+00	Mindy4b Mst1 Retreg2
Bone: stiffness	4554.23	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: tissue strength	2995.95	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular number	5387.39	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular spacing	2669.39	3	3	60	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: trabecular thickness	4257.4	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: trabecular tissue density	4866.8	3	3	60	0	1.00e+00	Mst1 Ndufb9 Retreg2
Breakpoint value in progressive ratio session	18809.48	2	1	20	0	1.00e+00	Mst1 Retreg2
Distance traveled before self-admin	12639.47	4	1	20	-1	2.25e-03	Mst1 Ndufb9 Retreg2 Zfp575
Distance traveled after self-admin	16235.57	2	1	20	0	1.00e+00	Retreg2 Zfp575
Delta time in closed arm before/after self-admin	87.3	3	1	20	0	1.00e+00	Mst1 Ndufb9 Retreg2
Delta time in open arm before/after self-admin	7570.03	2	1	20	0	1.00e+00	Mst1 Retreg2
Diff in mean of infusions in LGA sessions	12226.72	3	2	40	0	1.00e+00	Mst1 Ndufb9 Retreg2
Extinction: sum of active levers before priming	7122.61	4	3	60	-1	4.18e-03	Mindy4b Mst1 Ndufb9 Retreg2
Active lever presses in extinction session 6	384.74	2	2	40	0	1.00e+00	Mst1 Retreg2
Delta distance traveled before/after self-admin	1485.64	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Delta ambulatory time before/after self-admin	15429.45	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Time in closed arm before self-admin	13457.43	2	2	40	0	1.00e+00	Mst1 Retreg2
Time in closed arm after self-admin	2326.29	2	2	40	0	1.00e+00	Mst1 Retreg2
Time in open arm before self-admin	1770.79	5	2	40	1	1.07e-04	Mindy4b Mst1 Ndufb9 Retreg2 Zfp575
Time in open arm after self-admin	200.08	3	3	60	0	1.00e+00	Mst1 Ndufb9 Retreg2
Sum of active levers in priming session hrs 5-6	496.26	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Time to tail flick, vehicle, before self-admin	3352.74	4	2	40	-0.99	6.77e-03	Mindy4b Mst1 Ndufb9 Retreg2
Time to tail flick, vehicle, after self-admin	10545.29	4	1	20	-1	8.78e-04	Mindy4b Ndufb9 Retreg2 Zfp575
Time to tail flick, test, before self-admin	2050.3	4	2	40	1	3.93e-04	Mst1 Ndufb9 Retreg2 Zfp575
Time to tail flick, test, after self-admin	380.09	4	3	60	-0.94	5.55e-02	Mindy4b Mst1 Ndufb9 Retreg2
Delta time to tail flick, vehicle, before/after SA	3286.48	3	2	40	0	1.00e+00	Mindy4b Mst1 Retreg2
Delta time to tail flick, test, before/after SA	3933.87	4	2	40	-1	2.59e-03	Mindy4b Mst1 Ndufb9 Retreg2
Ambulatory time before self-admin	78874.38	1	1	20	0	1.00e+00	Retreg2
Ambulatory time after self-admin	13311.39	2	1	20	0	1.00e+00	Mst1 Retreg2
Total heroin consumption	240.55	1	1	20	0	1.00e+00	Retreg2
Area under the delay curve	12400.09	2	1	20	0	1.00e+00	Mindy4b Retreg2
Delay disc. indifference point, 0s delay	1084.93	2	1	20	0	1.00e+00	Mindy4b Retreg2
Delay disc. indifference point, 16s delay	10984.61	2	1	20	0	1.00e+00	Mindy4b Retreg2
Delay disc. indifference point, 2s delay	83.07	2	1	20	0	1.00e+00	Mindy4b Retreg2
Delay disc. indifference point, 24s delay	32437.06	1	1	20	0	1.00e+00	Retreg2
Delay disc. indifference point, 4s delay	163.92	4	1	20	0.96	4.42e-02	Mindy4b Mst1 Ndufb9 Retreg2
Delay disc. indifference point, 8s delay	33362.4	1	1	20	0	1.00e+00	Retreg2
Delay discount exponential model param	8465.49	2	1	20	0	1.00e+00	Mindy4b Retreg2
Delay discount hyperbolic model param	6145.01	2	1	20	0	1.00e+00	Mindy4b Retreg2
Fecal boli incidents, locomotor time 1	61202.36	1	1	20	0	1.00e+00	Retreg2
Change in fecal boli incidents, locomotor task	1904.41	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Time >=10cm from walls, locomotor time 1	4347.04	3	1	20	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Bouts of movement, locomotor time 1	5395.51	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Total resting periods, locomotor time 1	2793.59	1	1	20	0	1.00e+00	Retreg2
Rest time, locomotor task time 1	11183.83	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Distance moved, locomotor task time 1	34443.92	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Vertical activity count, locomotor time 1	71180.23	2	1	20	0	1.00e+00	Retreg2 Zfp575
Time >=10cm from walls, locomotor time 2	35595.55	2	2	40	0	1.00e+00	Mindy4b Retreg2
Bouts of movement, locomotor time 2	41021.38	2	1	20	0	1.00e+00	Mindy4b Retreg2
Total resting periods, locomotor time 2	49524.91	2	1	20	0	1.00e+00	Mindy4b Retreg2
Rest time, locomotor task time 2	12756.26	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Distance moved, locomotor task time 2	4245.69	2	1	20	0	1.00e+00	Mindy4b Retreg2
Vertical activity count, locomotor time 2	26790.07	2	2	40	0	1.00e+00	Mindy4b Retreg2
Weight adjusted by age	23614.28	3	2	40	0	1.00e+00	Ndufb9 Retreg2 Zfp575
Seeking ratio, delayed vs. immediate footshock	4491.19	3	1	20	0	1.00e+00	Mindy4b Retreg2 Zfp575
Locomotion in novel chamber	1993.33	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Locomotion in novel chamber post-restriction	21811.96	3	1	20	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Progressive ratio	22646.19	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Food seeking constrained by brief footshock	631.71	3	1	20	0	1.00e+00	Ndufb9 Retreg2 Zfp575
Seeking ratio, punishment vs. effort	20653.58	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Run reversals in cocaine runway, females	9406.04	1	1	20	0	1.00e+00	Retreg2
Run reversals in cocaine runway, males	3884.61	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Latency to leave start box in cocaine runway	16290.75	1	1	20	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, F	2400.69	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Latency to leave start box in cocaine runway, M	582.13	3	1	20	0	1.00e+00	Ndufb9 Retreg2 Zfp575
Co content in liver	1133.25	1	1	20	0	1.00e+00	Retreg2
Cu content in liver	28.08	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Fe content in liver	1344.53	1	1	20	0	1.00e+00	Retreg2
K content in liver	1519.62	1	1	20	0	1.00e+00	Retreg2
Mg content in liver	6026.97	1	1	20	0	1.00e+00	Retreg2
Mn content in liver	537.3	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Na content in liver	2013.84	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Rb content in liver	71.08	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Se content in liver	8.63	1	0	0	0	1.00e+00	Ndufb9
Zn content in liver	1887.46	2	2	40	0	1.00e+00	Ndufb9 Retreg2

Associations by panel

Tissue	RNA modality	# hits	Avg chisq
Adipose	alternative polyA	0	1.11
Adipose	alternative TSS	0	1.13
Adipose	gene expression	0	1.11
Adipose	isoform ratio	0	1.1
Adipose	intron excision ratio	0	1.21
Adipose	mRNA stability	1	1.12
BLA	alternative polyA	0	1.15
BLA	alternative TSS	0	1.03
BLA	gene expression	0	1.11
BLA	isoform ratio	0	1.16
BLA	intron excision ratio	0	1.1
BLA	mRNA stability	0	1.11
Brain	alternative polyA	0	1.15
Brain	alternative TSS	0	1
Brain	gene expression	0	1.1
Brain	isoform ratio	0	1.1
Brain	intron excision ratio	0	1.1
Brain	mRNA stability	0	1.11
Eye	alternative polyA	0	1.12
Eye	alternative TSS	0	0.97
Eye	gene expression	0	1.16
Eye	isoform ratio	0	1.29
Eye	intron excision ratio	0	0.96
Eye	mRNA stability	0	1.15
IC	alternative polyA	0	1.15
IC	alternative TSS	0	1.05
IC	gene expression	0	1.12
IC	isoform ratio	0	1.15
IC	intron excision ratio	0	1.12
IC	mRNA stability	0	1.11
IL	alternative polyA	0	1.22
IL	alternative TSS	0	0.88
IL	gene expression	0	1.11
IL	isoform ratio	0	1.18
IL	intron excision ratio	0	1.01
IL	mRNA stability	0	1.13
LHb	alternative polyA	0	1.26
LHb	alternative TSS	0	1
LHb	gene expression	0	1.08
LHb	isoform ratio	0	1.16
LHb	intron excision ratio	0	0.97
LHb	mRNA stability	0	1.21
Liver	alternative polyA	0	1.07
Liver	alternative TSS	0	1.06
Liver	gene expression	0	1.12
Liver	isoform ratio	1	1.18
Liver	intron excision ratio	0	1.07
Liver	mRNA stability	0	1.16
NAcc	alternative polyA	1	15.91
NAcc	alternative TSS	0	1.12
NAcc	gene expression	0	1.12
NAcc	isoform ratio	0	1.15
NAcc	intron excision ratio	1	1.12
NAcc	mRNA stability	0	1.14
OFC	alternative polyA	0	1.12
OFC	alternative TSS	0	1.03
OFC	gene expression	0	1.11
OFC	isoform ratio	0	1.1
OFC	intron excision ratio	0	0.96
OFC	mRNA stability	0	1.11
PL	alternative polyA	0	1.22
PL	alternative TSS	0	1.06
PL	gene expression	0	1.11
PL	isoform ratio	0	1.12
PL	intron excision ratio	0	1.12
PL	mRNA stability	1	1.16
pVTA	alternative polyA	0	1.19
pVTA	alternative TSS	0	1.1
pVTA	gene expression	0	1.11
pVTA	isoform ratio	0	1.15
pVTA	intron excision ratio	0	1.11
pVTA	mRNA stability	0	1.15
RMTg	alternative polyA	0	1.18
RMTg	alternative TSS	0	1.14
RMTg	gene expression	0	1.17
RMTg	isoform ratio	0	1.21
RMTg	intron excision ratio	0	0.92
RMTg	mRNA stability	0	1.17