Project: tautz
1 significantly associated model · 1 unique gene
| # | chr | p0 | p1 | # assoc genes | # joint models | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 10 | 55699574 | 57088265 | 1 | 1 | 3.1e-07 | 4.3e-06 | 0.99 | 100 | Wscd1 |
p0: physical position of the start of the locus. p1: physical position of the end of the locus. # joint models: number of models selected by step-wise conditional analysis.
| Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
|---|---|---|---|---|---|---|---|
| dissection: UMAP 1 of all traits | 1.2 | 1 | 0 | 0 | 0 | 1 | Wscd1 |
| body_g | 1.7 | 1 | 0 | 0 | 0 | 1 | Wscd1 |
| Tibia length in mm | 2.5 | 1 | 0 | 0 | 0 | 1 | Wscd1 |
| sol weight in grams | 3.0 | 1 | 0 | 0 | 0 | 1 | Wscd1 |
| reaction_time_devmedrt_slope | 4.3 | 1 | 0 | 0 | 0 | 1 | Wscd1 |
| pavca_mi_d1_prob_lev | 3.9 | 1 | 0 | 0 | 0 | 1 | Wscd1 |
| pavca_mi_d1_avg_lev_lat | 3.0 | 1 | 0 | 0 | 0 | 1 | Wscd1 |
| Cortical porosity | 3.8 | 1 | 0 | 0 | 0 | 1 | Wscd1 |
| tautz: manual_spc15 | 5.4 | 1 | 0 | 0 | 0 | 1 | Wscd1 |
| tautz: manual_spc9 | 2.7 | 1 | 0 | 0 | 0 | 1 | Wscd1 |
| tautz: manual_spc8 | 2.8 | 1 | 0 | 0 | 0 | 1 | Wscd1 |
| tautz: manual_mpc12 | 5.3 | 1 | 0 | 0 | 0 | 1 | Wscd1 |
| tautz: manual_spc23 | 6.3 | 1 | 0 | 0 | 0 | 1 | Wscd1 |
| tautz: manual_spc19 | 5.5 | 1 | 0 | 0 | 0 | 1 | Wscd1 |
| tautz: manual_mpc1 | 4.5 | 1 | 0 | 0 | 0 | 1 | Wscd1 |
chisq ratio: Average Chi2 statistic for the selected genes in the secondary trait, divided by the average statistic for all genes in the secondary trait. # genes+: Shared significant genes at Bonferroni correction. # genes++: Shared significant genes at transcriptome-wide significance. % genes++: Number of [++] genes as a percentage of primary trait’s total joint genes. corr: Correlation of effect sizes across the [+] genes.
| tissue | modality | # hits | % hits/tests | avg chisq |
|---|---|---|---|---|
| Adipose | alternative polyA | 0 | 0.000 | 1.4 |
| Adipose | alternative TSS | 0 | 0.000 | 1.4 |
| Adipose | gene expression | 1 | 0.012 | 1.4 |
| Adipose | isoform ratio | 0 | 0.000 | 1.4 |
| Adipose | intron excision ratio | 0 | 0.000 | 1.4 |
| Adipose | mRNA stability | 0 | 0.000 | 1.4 |
| BLA | alternative polyA | 0 | 0.000 | 1.3 |
| BLA | alternative TSS | 0 | 0.000 | 1.5 |
| BLA | gene expression | 0 | 0.000 | 1.4 |
| BLA | isoform ratio | 0 | 0.000 | 1.3 |
| BLA | intron excision ratio | 0 | 0.000 | 1.3 |
| BLA | mRNA stability | 0 | 0.000 | 1.4 |
| Brain | alternative polyA | 0 | 0.000 | 1.4 |
| Brain | alternative TSS | 0 | 0.000 | 1.3 |
| Brain | gene expression | 0 | 0.000 | 1.4 |
| Brain | isoform ratio | 0 | 0.000 | 1.3 |
| Brain | intron excision ratio | 0 | 0.000 | 1.3 |
| Brain | mRNA stability | 0 | 0.000 | 1.4 |
| Eye | alternative polyA | 0 | 0.000 | 1.3 |
| Eye | alternative TSS | 0 | 0.000 | 1.5 |
| Eye | gene expression | 0 | 0.000 | 1.3 |
| Eye | isoform ratio | 0 | 0.000 | 1.4 |
| Eye | intron excision ratio | 0 | 0.000 | 1.5 |
| Eye | mRNA stability | 0 | 0.000 | 1.9 |
| IL | alternative polyA | 0 | 0.000 | 1.3 |
| IL | alternative TSS | 0 | 0.000 | 1.2 |
| IL | gene expression | 0 | 0.000 | 1.4 |
| IL | isoform ratio | 0 | 0.000 | 1.2 |
| IL | intron excision ratio | 0 | 0.000 | 1.2 |
| IL | mRNA stability | 0 | 0.000 | 1.4 |
| LHb | alternative polyA | 0 | 0.000 | 1.2 |
| LHb | alternative TSS | 0 | 0.000 | 1.5 |
| LHb | gene expression | 0 | 0.000 | 1.4 |
| LHb | isoform ratio | 0 | 0.000 | 1.2 |
| LHb | intron excision ratio | 0 | 0.000 | 1.3 |
| LHb | mRNA stability | 0 | 0.000 | 1.4 |
| Liver | alternative polyA | 0 | 0.000 | 1.3 |
| Liver | alternative TSS | 0 | 0.000 | 1.4 |
| Liver | gene expression | 0 | 0.000 | 1.4 |
| Liver | isoform ratio | 0 | 0.000 | 1.4 |
| Liver | intron excision ratio | 0 | 0.000 | 1.2 |
| Liver | mRNA stability | 0 | 0.000 | 1.4 |
| NAcc | alternative polyA | 0 | 0.000 | 1.4 |
| NAcc | alternative TSS | 0 | 0.000 | 1.5 |
| NAcc | gene expression | 0 | 0.000 | 1.5 |
| NAcc | isoform ratio | 0 | 0.000 | 1.3 |
| NAcc | intron excision ratio | 0 | 0.000 | 1.3 |
| NAcc | mRNA stability | 0 | 0.000 | 1.4 |
| NAcc2 | alternative polyA | 0 | 0.000 | 1.4 |
| NAcc2 | alternative TSS | 0 | 0.000 | 1.5 |
| NAcc2 | gene expression | 0 | 0.000 | 1.5 |
| NAcc2 | isoform ratio | 0 | 0.000 | 1.3 |
| NAcc2 | intron excision ratio | 0 | 0.000 | 1.3 |
| NAcc2 | mRNA stability | 0 | 0.000 | 1.3 |
| OFC | alternative polyA | 0 | 0.000 | 1.3 |
| OFC | alternative TSS | 0 | 0.000 | 1.5 |
| OFC | gene expression | 0 | 0.000 | 1.4 |
| OFC | isoform ratio | 0 | 0.000 | 1.2 |
| OFC | intron excision ratio | 0 | 0.000 | 1.2 |
| OFC | mRNA stability | 0 | 0.000 | 1.3 |
| PL | alternative polyA | 0 | 0.000 | 1.3 |
| PL | alternative TSS | 0 | 0.000 | 1.3 |
| PL | gene expression | 0 | 0.000 | 1.4 |
| PL | isoform ratio | 0 | 0.000 | 1.2 |
| PL | intron excision ratio | 0 | 0.000 | 1.3 |
| PL | mRNA stability | 0 | 0.000 | 1.4 |
| PL2 | alternative polyA | 0 | 0.000 | 1.2 |
| PL2 | alternative TSS | 0 | 0.000 | 1.4 |
| PL2 | gene expression | 0 | 0.000 | 1.4 |
| PL2 | isoform ratio | 0 | 0.000 | 1.3 |
| PL2 | intron excision ratio | 0 | 0.000 | 1.3 |
| PL2 | mRNA stability | 0 | 0.000 | 1.3 |
avg chisq: Average Chi2 (squared Z-score) across all models in this panel for this trait.