Intermittent access intake escalation 2

Average intermittent access infusions from days 12-15 minus average from days 1-3

Tags: Behavior · Intermittent access · Cocaine

Project: p50_paul_meyer_2020

4 loci · 4 genes with independent associations · 4 total associated genes

Significant Loci

# Chr Start pos End pos # assoc genes # joint models Best TWAS P Best GWAS P Cond GWAS P Joint genes
1 2 90636696 92031287 1 1 1.29e-07 1.38e-03 6.29e-01 Snx16
2 7 16845355 16970279 1 1 8.24e-11 NaN NA ENSRNOG00000064438
3 7 64797685 66194629 1 1 9.29e-08 4.09e-02 3.22e-16 Matn2
4 8 108584253 109479622 1 1 5.45e-08 3.22e-02 6.82e-07 Apeh

Pleiotropic Associations

Trait Chi2 ratio # genes+ # genes++ % genes++ Corr Corr P Genes
BMI with tail 2.94 1 0 0 0 1.00e+00 Snx16
BMI without tail 97.24 2 2 50 0 1.00e+00 Snx16 ENSRNOG00000064438
Body weight 8.09 2 1 25 0 1.00e+00 Snx16 ENSRNOG00000064438
Epididymis fat weight 136.19 1 1 25 0 1.00e+00 ENSRNOG00000064438
Glucose 6.57 1 0 0 0 1.00e+00 ENSRNOG00000064438
Heart weight 11.41 1 0 0 0 1.00e+00 ENSRNOG00000064438
Left kidney weight 62.74 1 1 25 0 1.00e+00 ENSRNOG00000064438
Right kidney weight 34.93 2 1 25 0 1.00e+00 Matn2 ENSRNOG00000064438
Tail length 52.78 2 2 50 0 1.00e+00 Snx16 ENSRNOG00000064438
Length with tail 3.31 2 0 0 0 1.00e+00 Snx16 ENSRNOG00000064438
Length without tail 120.15 1 1 25 0 1.00e+00 ENSRNOG00000064438
Liver weight, left 13.77 2 1 25 0 1.00e+00 Apeh ENSRNOG00000064438
Liver weight, right 9.6 1 0 0 0 1.00e+00 ENSRNOG00000064438
Parametrial fat weight 26.35 1 1 25 0 1.00e+00 ENSRNOG00000064438
Retroperitoneal fat weight 4.2 1 0 0 0 1.00e+00 ENSRNOG00000064438
Intraocular pressure 17.42 2 1 25 0 1.00e+00 Snx16 ENSRNOG00000064438
Extensor digitorum longus weight 23.69 2 2 50 0 1.00e+00 Snx16 ENSRNOG00000064438
Soleus weight 21.94 1 1 25 0 1.00e+00 ENSRNOG00000064438
Tibialis anterior weight 52.05 2 2 50 0 1.00e+00 Snx16 ENSRNOG00000064438
Tibia length 7.41 1 0 0 0 1.00e+00 ENSRNOG00000064438
Number of licking bursts 242.45 1 1 25 0 1.00e+00 ENSRNOG00000064438
Food consumed during 24 hour testing period 17.5 1 0 0 0 1.00e+00 ENSRNOG00000064438
Times rat made contact with spout 121.61 1 1 25 0 1.00e+00 ENSRNOG00000064438
Mean time between licks in bursts 90.53 1 1 25 0 1.00e+00 ENSRNOG00000064438
Mean num. licks in bursts 258.22 1 1 25 0 1.00e+00 ENSRNOG00000064438
Std. dev. time between licks in bursts 148.95 2 1 25 0 1.00e+00 Apeh ENSRNOG00000064438
Water consumed over 24 hours 5.74 1 0 0 0 1.00e+00 ENSRNOG00000064438
Indifference point 0 sec 21.27 1 1 25 0 1.00e+00 ENSRNOG00000064438
Indifference point AUC 41.66 2 1 25 0 1.00e+00 Snx16 ENSRNOG00000064438
Indifference point function ln k 4.41 1 0 0 0 1.00e+00 ENSRNOG00000064438
Indifference point function log k 4.41 1 0 0 0 1.00e+00 ENSRNOG00000064438
Delay discounting total patch changes 0 sec 20.12 1 1 25 0 1.00e+00 ENSRNOG00000064438
Delay discounting total patch changes 12 sec 156.88 1 1 25 0 1.00e+00 ENSRNOG00000064438
Delay discounting total patch changes 18 sec 96.16 3 1 25 0 1.00e+00 Snx16 Apeh ENSRNOG00000064438
Delay discounting total patch changes 24 sec 43.71 1 1 25 0 1.00e+00 ENSRNOG00000064438
Delay discounting total patch changes 6 sec 51.38 3 1 25 0 1.00e+00 Snx16 Apeh ENSRNOG00000064438
Delay discounting time to switch 0 sec 11.43 1 0 0 0 1.00e+00 Snx16
Delay discounting water rate 0 sec 11.76 1 0 0 0 1.00e+00 ENSRNOG00000064438
Delay discounting water rate 12 sec 44.18 1 1 25 0 1.00e+00 ENSRNOG00000064438
Delay discounting water rate 18 sec 10.52 1 0 0 0 1.00e+00 ENSRNOG00000064438
Delay discounting water rate 24 sec 100.9 1 1 25 0 1.00e+00 ENSRNOG00000064438
Delay discounting water rate 6 sec 70.2 1 1 25 0 1.00e+00 ENSRNOG00000064438
Locomotor testing distance 9.22 2 0 0 0 1.00e+00 Matn2 ENSRNOG00000064438
Locomotor testing rearing 23.89 1 1 25 0 1.00e+00 ENSRNOG00000064438
Light reinforcement 1 84.13 1 1 25 0 1.00e+00 ENSRNOG00000064438
Light reinforcement 2 6.68 1 0 0 0 1.00e+00 Matn2
Reaction time number correct 7.52 2 0 0 0 1.00e+00 Snx16 ENSRNOG00000064438
Reaction time mean minus median 5.82 1 0 0 0 1.00e+00 Snx16
Reaction time mean minus median AUC 6.13 1 0 0 0 1.00e+00 Snx16
Reaction time num false alarms 48.89 2 1 25 0 1.00e+00 Snx16 ENSRNOG00000064438
Reaction time num false alarms AUC 128.16 1 1 25 0 1.00e+00 ENSRNOG00000064438
Reaction time trials correct on left 7.52 2 0 0 0 1.00e+00 Snx16 ENSRNOG00000064438
Reaction time trials on left 7.8 2 0 0 0 1.00e+00 Snx16 ENSRNOG00000064438
Reaction time mean 62.45 1 1 25 0 1.00e+00 ENSRNOG00000064438
Reaction time mean AUC 89.09 1 1 25 0 1.00e+00 ENSRNOG00000064438
Median of all reaction times 80.24 1 1 25 0 1.00e+00 ENSRNOG00000064438
Reaction time omissions 7.27 1 0 0 0 1.00e+00 Snx16
Reaction time false alarm rate 104.16 1 1 25 0 1.00e+00 ENSRNOG00000064438
Reaction time premature initiation rate 47.3 1 1 25 0 1.00e+00 ENSRNOG00000064438
Reaction time premature initiations 49.75 1 1 25 0 1.00e+00 ENSRNOG00000064438
Std. dev. reaction times 13.12 3 1 25 0 1.00e+00 Matn2 Snx16 ENSRNOG00000064438
Reaction time trials completed 7.8 2 0 0 0 1.00e+00 Snx16 ENSRNOG00000064438
Reaction time trials AUC 10.88 2 0 0 0 1.00e+00 Snx16 ENSRNOG00000064438
Social response proportion 15.64 1 0 0 0 1.00e+00 Matn2
Social responses 42.33 3 1 25 0 1.00e+00 Matn2 Snx16 ENSRNOG00000064438
Social time 7.34 2 0 0 0 1.00e+00 Matn2 ENSRNOG00000064438
Cocaine response after cond. corrected 135.65 1 1 25 0 1.00e+00 ENSRNOG00000064438
Cocaine response after cond. not corrected 91.97 2 1 25 0 1.00e+00 Matn2 ENSRNOG00000064438
Cocaine response before conditioning 28.56 1 1 25 0 1.00e+00 ENSRNOG00000064438
Saline control response 50.64 1 1 25 0 1.00e+00 ENSRNOG00000064438
Condit. Reinf. active minus inactive responses 46.4 1 1 25 0 1.00e+00 ENSRNOG00000064438
Condit. Reinf. active-inactive response ratio 68.68 1 1 25 0 1.00e+00 ENSRNOG00000064438
Condit. Reinf. active responses 8.33 2 0 0 0 1.00e+00 Matn2 ENSRNOG00000064438
Condit. Reinf. inactive responses 20.59 1 0 0 0 1.00e+00 ENSRNOG00000064438
Condit. Reinf. lever reinforcers received 5.86 1 0 0 0 1.00e+00 Matn2
Pavlov. Cond. lever latency 60.53 1 1 25 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. magazine entry latency 173.36 1 1 25 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. change in total contacts 216.69 1 1 25 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. index score 102.16 1 1 25 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. latency score 110.33 1 1 25 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. lever contacts 29.45 1 1 25 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. magazine entry number 244.87 1 1 25 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. intertrial magazine entries 106.17 1 1 25 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. lever-magazine prob. diff. 90.64 1 1 25 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. response bias 51.3 1 1 25 0 1.00e+00 ENSRNOG00000064438
Conditioned reinforcement - actives 18.52 1 0 0 0 1.00e+00 ENSRNOG00000064438
Conditioned reinforcement - inactives 32.17 1 1 25 0 1.00e+00 Apeh
Conditioned locomotion 7.56 2 0 0 0 1.00e+00 Apeh ENSRNOG00000064438
Intermittent access intake day 1-15 change 39.01 4 2 50 0.97 2.93e-02 Matn2 Snx16 Apeh ENSRNOG00000064438
Intermittent access intake escalation 46.62 4 1 25 0.94 5.99e-02 Matn2 Snx16 Apeh ENSRNOG00000064438
Intermitt. access day 1 inactive lever presses 30.61 1 1 25 0 1.00e+00 ENSRNOG00000064438
Intermitt. access day 15 inactive lever presses 27.39 1 1 25 0 1.00e+00 Apeh
Intermitt. access escalation Index 9.28 2 0 0 0 1.00e+00 Matn2 ENSRNOG00000064438
Intermittent access day 1 total infusions 52.87 1 1 25 0 1.00e+00 ENSRNOG00000064438
Intermittent access terminal intake (last 3 days) 6.27 1 0 0 0 1.00e+00 Snx16
Intermittent access day 1 locomotion 27.14 1 1 25 0 1.00e+00 ENSRNOG00000064438
Intermittent access day 15 total locomotion 7.9 1 0 0 0 1.00e+00 Matn2
Intermittent access standard deviation 27.04 2 1 25 0 1.00e+00 Snx16 Apeh
Cocaine induced anxiety 10.21 2 0 0 0 1.00e+00 Snx16 Apeh
Post-drug Anxiety 26.41 2 1 25 0 1.00e+00 Snx16 ENSRNOG00000064438
Incentive Sensitization - Responses 8.7 1 0 0 0 1.00e+00 Apeh
Incentive Sensitization - Breakpoint 8.81 1 0 0 0 1.00e+00 Apeh
Progressive ratio test 1 active lever presses 9.91 3 0 0 0 1.00e+00 Snx16 Apeh ENSRNOG00000064438
Progressive ratio test 1 breakpoint 10.3 2 0 0 0 1.00e+00 Apeh ENSRNOG00000064438
Progressive ratio test 1 inactive lever presses 9.17 3 0 0 0 1.00e+00 Matn2 Apeh ENSRNOG00000064438
Progressive ratio test 2 active lever presses 12.24 1 0 0 0 1.00e+00 ENSRNOG00000064438
Progressive ratio test 2 breakpoint 61.59 1 1 25 0 1.00e+00 ENSRNOG00000064438
Progressive ratio test 2 inactive lever presses 24.18 2 1 25 0 1.00e+00 Matn2 Apeh
Total sessions with >9 infusions 12.38 2 0 0 0 1.00e+00 Matn2 Apeh
Short access day 1 total inactive lever presses 7.7 1 0 0 0 1.00e+00 Apeh
Short access day 10 total inactive lever presses 20.49 3 1 25 0 1.00e+00 Matn2 Apeh ENSRNOG00000064438
Short access day 10 total infusions 24.04 1 1 25 0 1.00e+00 ENSRNOG00000064438
Short access day 1 locomotion 17.24 1 0 0 0 1.00e+00 ENSRNOG00000064438
Short access day 10 total locomotion 6.38 1 0 0 0 1.00e+00 Apeh
Short access total locomotion 10.65 1 0 0 0 1.00e+00 Apeh
Compulsive drug intake 20.13 3 1 25 0 1.00e+00 Matn2 Apeh ENSRNOG00000064438
One hour access (0.3 mA shock) 10.45 1 0 0 0 1.00e+00 ENSRNOG00000064438
Number of responses in last shaping day 12 1 0 0 0 1.00e+00 Apeh
Context. condit. distance diff. score 240.19 1 1 25 0 1.00e+00 ENSRNOG00000064438
Locomotion velocity, session 1 190.79 1 1 25 0 1.00e+00 ENSRNOG00000064438
Locomotion distance, session 1 609.62 1 1 25 0 1.00e+00 ENSRNOG00000064438
Locomotion velocity, session 2 139.57 1 1 25 0 1.00e+00 ENSRNOG00000064438
Locomotion distance, session 2 1269.9 1 1 25 0 1.00e+00 ENSRNOG00000064438
Locomotion velocity, session 3 178.89 1 1 25 0 1.00e+00 ENSRNOG00000064438
Locomotion distance, session 3 117.54 1 1 25 0 1.00e+00 ENSRNOG00000064438
Stereotopy head waving bouts, day 3 8.83 1 0 0 0 1.00e+00 ENSRNOG00000064438
Stereotopy head waving duration, day 3 33.17 1 1 25 0 1.00e+00 ENSRNOG00000064438
Locomotion velocity, session 7 98.87 1 1 25 0 1.00e+00 ENSRNOG00000064438
Locomotion distance, session 7 31.83 1 1 25 0 1.00e+00 ENSRNOG00000064438
Stereotopy head waving bouts, day 7 68.43 1 1 25 0 1.00e+00 ENSRNOG00000064438
Stereotopy head waving duration, day 7 102.2 1 1 25 0 1.00e+00 ENSRNOG00000064438
Locomotion distance, session 8 171.7 1 1 25 0 1.00e+00 ENSRNOG00000064438
Degree of sensitization distance 198.53 1 1 25 0 1.00e+00 ENSRNOG00000064438
Degree of sensitization stereotypy 37.55 1 1 25 0 1.00e+00 ENSRNOG00000064438
Condit. Reinf. active minus inactive responses 5.6 1 0 0 0 1.00e+00 ENSRNOG00000064438
Condit. Reinf. active-inactive response ratio 107.34 1 1 25 0 1.00e+00 ENSRNOG00000064438
Condit. Reinf. active responses 20.03 1 0 0 0 1.00e+00 ENSRNOG00000064438
Condit. Reinf. inactive responses 17.25 1 0 0 0 1.00e+00 ENSRNOG00000064438
Incentive salience index mean 15.58 1 0 0 0 1.00e+00 ENSRNOG00000064438
Condit. Reinf. lever presses 35.11 1 1 25 0 1.00e+00 ENSRNOG00000064438
Time in familiar zone, hab. session 1 14.36 2 0 0 0 1.00e+00 Snx16 ENSRNOG00000064438
Time in novel zone, hab. session 1 17.41 1 0 0 0 1.00e+00 ENSRNOG00000064438
Total zone transitions, hab. session 1 673.79 1 1 25 0 1.00e+00 ENSRNOG00000064438
Total locomotion distance, hab. session 1 142.59 2 1 25 0 1.00e+00 Matn2 ENSRNOG00000064438
Locomotion velocity, hab. session 1 349.52 1 1 25 0 1.00e+00 ENSRNOG00000064438
Time in familiar zone, hab. session 2 27.48 2 1 25 0 1.00e+00 Snx16 ENSRNOG00000064438
Time in novel zone, hab. session 2 58.43 1 1 25 0 1.00e+00 ENSRNOG00000064438
Total zone transitions, hab. session 2 421.23 1 1 25 0 1.00e+00 ENSRNOG00000064438
Total locomotion distance, hab. session 2 214.28 1 1 25 0 1.00e+00 ENSRNOG00000064438
Locomotion velocity, hab. session 2 224.99 1 1 25 0 1.00e+00 ENSRNOG00000064438
Novel to familiar place preference ratio 6.25 1 0 0 0 1.00e+00 Apeh
Novelty place preference 7.01 1 0 0 0 1.00e+00 Apeh
Time in novel zone, NPP test 6.78 1 0 0 0 1.00e+00 Apeh
Total zone transitions, NPP test 376.15 1 1 25 0 1.00e+00 ENSRNOG00000064438
Total locomotion distance, NPP test 269.3 1 1 25 0 1.00e+00 ENSRNOG00000064438
Locomotion velocity, NPP test 317.81 1 1 25 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. lever latency 9.32 1 0 0 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. magazine entry latency 50.62 2 1 25 0 1.00e+00 Apeh ENSRNOG00000064438
Pavlov. Cond. change in total contacts 40.12 1 1 25 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. index score 51.85 1 1 25 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. latency score 16.59 1 0 0 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. lever contacts 16.14 1 0 0 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. magazine entry number 61.65 1 1 25 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. intertrial magazine entries 5.98 1 0 0 0 1.00e+00 Matn2
Pavlov. Cond. lever-magazine prob. diff. 88.12 1 1 25 0 1.00e+00 ENSRNOG00000064438
Pavlov. Cond. response bias 28.84 2 1 25 0 1.00e+00 Apeh ENSRNOG00000064438
Bone: apparent density 31.19 1 1 25 0 1.00e+00 ENSRNOG00000064438
Bone surface 41.33 1 1 25 0 1.00e+00 ENSRNOG00000064438
Bone volume 47.66 1 1 25 0 1.00e+00 ENSRNOG00000064438
Bone: connectivity density 8.5 1 0 0 0 1.00e+00 ENSRNOG00000064438
Bone: cortical porosity 188.54 1 1 25 0 1.00e+00 ENSRNOG00000064438
Bone: cortical porosity 155.79 1 1 25 0 1.00e+00 ENSRNOG00000064438
Bone: cortical thickness 8.79 1 0 0 0 1.00e+00 ENSRNOG00000064438
Bone: cortical thickness 17.92 1 0 0 0 1.00e+00 ENSRNOG00000064438
Bone: elastic displacement 28.18 1 1 25 0 1.00e+00 ENSRNOG00000064438
Bone: endosteal estimation 11.13 2 1 25 0 1.00e+00 Snx16 ENSRNOG00000064438
Bone: final force 57.36 1 1 25 0 1.00e+00 ENSRNOG00000064438
Bone: final moment 45.56 1 1 25 0 1.00e+00 ENSRNOG00000064438
Bone: marrow area 9.8 2 1 25 0 1.00e+00 Snx16 ENSRNOG00000064438
Bone: maximum force 60.3 1 1 25 0 1.00e+00 ENSRNOG00000064438
Bone: maximum moment 41.21 1 1 25 0 1.00e+00 ENSRNOG00000064438
Bone: minimum diameter 47.12 2 1 25 0 1.00e+00 Snx16 ENSRNOG00000064438
Bone: periosteal estimation 7.21 2 0 0 0 1.00e+00 Snx16 ENSRNOG00000064438
Bone: periosteal perimeter 8.75 1 0 0 0 1.00e+00 ENSRNOG00000064438
Bone: post-yield work 124.34 1 1 25 0 1.00e+00 ENSRNOG00000064438
Bone: stiffness 136.78 1 1 25 0 1.00e+00 ENSRNOG00000064438
Bone: tissue strength 135.98 1 1 25 0 1.00e+00 ENSRNOG00000064438
Bone: trabecular number 64.11 1 1 25 0 1.00e+00 ENSRNOG00000064438
Bone: trabecular spacing 5.66 1 0 0 0 1.00e+00 ENSRNOG00000064438
Bone: trabecular thickness 13.82 1 0 0 0 1.00e+00 ENSRNOG00000064438
Bone: trabecular tissue density 66.58 1 1 25 0 1.00e+00 ENSRNOG00000064438
Breakpoint value in progressive ratio session 13.57 1 0 0 0 1.00e+00 Matn2
Distance traveled before self-admin 14.79 2 0 0 0 1.00e+00 Snx16 ENSRNOG00000064438
Distance traveled after self-admin 7.3 1 0 0 0 1.00e+00 Snx16
Delta time in closed arm before/after self-admin 8.57 1 0 0 0 1.00e+00 Snx16
Delta time in open arm before/after self-admin 40.25 1 1 25 0 1.00e+00 ENSRNOG00000064438
Diff in mean of infusions in LGA sessions 9.81 1 0 0 0 1.00e+00 Snx16
Extinction: sum of active levers before priming 12.19 1 0 0 0 1.00e+00 ENSRNOG00000064438
Active lever presses in extinction session 6 8.79 2 0 0 0 1.00e+00 Snx16 ENSRNOG00000064438
Delta distance traveled before/after self-admin 11.33 1 0 0 0 1.00e+00 ENSRNOG00000064438
Time in closed arm before self-admin 77.96 1 1 25 0 1.00e+00 ENSRNOG00000064438
Time in closed arm after self-admin 40.16 1 1 25 0 1.00e+00 ENSRNOG00000064438
Time in open arm after self-admin 31.26 1 1 25 0 1.00e+00 ENSRNOG00000064438
Time to tail flick, vehicle, before self-admin 11.76 2 0 0 0 1.00e+00 Matn2 Snx16
Time to tail flick, test, before self-admin 20.61 1 0 0 0 1.00e+00 Snx16
Delta time to tail flick, vehicle, before/after SA 12.49 2 0 0 0 1.00e+00 Matn2 ENSRNOG00000064438
Delta time to tail flick, test, before/after SA 20.03 1 0 0 0 1.00e+00 ENSRNOG00000064438
Ambulatory time before self-admin 10.3 1 0 0 0 1.00e+00 Apeh
Delay disc. indifference point, 24s delay 7.73 1 0 0 0 1.00e+00 Matn2
Delay disc. indifference point, 8s delay 8.92 1 0 0 0 1.00e+00 Snx16
Fecal boli incidents, locomotor time 1 9.62 2 0 0 0 1.00e+00 Snx16 ENSRNOG00000064438
Change in fecal boli incidents, locomotor task 8.82 1 0 0 0 1.00e+00 ENSRNOG00000064438
Time >=10cm from walls, locomotor time 1 16.73 2 0 0 0 1.00e+00 Snx16 ENSRNOG00000064438
Bouts of movement, locomotor time 1 10.54 1 0 0 0 1.00e+00 Snx16
Time >=10cm from walls, locomotor time 2 18.86 2 1 25 0 1.00e+00 Matn2 ENSRNOG00000064438
Total resting periods, locomotor time 2 6.01 1 0 0 0 1.00e+00 ENSRNOG00000064438
Rest time, locomotor task time 2 7.71 2 0 0 0 1.00e+00 Matn2 ENSRNOG00000064438
Distance moved, locomotor task time 2 11.27 2 0 0 0 1.00e+00 Matn2 ENSRNOG00000064438
Vertical activity count, locomotor time 2 9.54 1 0 0 0 1.00e+00 Matn2
Weight adjusted by age 37.65 2 2 50 0 1.00e+00 Snx16 ENSRNOG00000064438
Seeking ratio, delayed vs. immediate footshock 22.65 1 1 25 0 1.00e+00 Snx16
Locomotion in novel chamber 10.2 1 0 0 0 1.00e+00 ENSRNOG00000064438
Food seeking constrained by brief footshock 16.73 1 0 0 0 1.00e+00 Snx16
Seeking ratio, punishment vs. effort 7.36 1 0 0 0 1.00e+00 Matn2
Run reversals in cocaine runway, females 8.56 1 0 0 0 1.00e+00 Matn2
Run reversals in cocaine runway, males 23.4 2 1 25 0 1.00e+00 Matn2 ENSRNOG00000064438
Latency to leave start box in cocaine runway 14.04 2 0 0 0 1.00e+00 Matn2 ENSRNOG00000064438
Latency to leave start box in cocaine runway, F 6.38 1 0 0 0 1.00e+00 Matn2
Cd content in liver 239.3 1 1 25 0 1.00e+00 ENSRNOG00000064438
Co content in liver 143.3 1 1 25 0 1.00e+00 ENSRNOG00000064438
Fe content in liver 10.34 1 0 0 0 1.00e+00 ENSRNOG00000064438
K content in liver 87.29 1 1 25 0 1.00e+00 ENSRNOG00000064438
Mn content in liver 207.1 1 1 25 0 1.00e+00 ENSRNOG00000064438
Rb content in liver 31.44 1 1 25 0 1.00e+00 ENSRNOG00000064438
Se content in liver 46.95 1 1 25 0 1.00e+00 ENSRNOG00000064438
Zn content in liver 45.96 1 1 25 0 1.00e+00 ENSRNOG00000064438

Associations by panel

Tissue RNA modality # hits % hits/tests Avg chisq
Adipose alternative polyA 0 0 0.93
Adipose alternative TSS 0 0 0.98
Adipose gene expression 1 0 0.99
Adipose isoform ratio 0 0 0.96
Adipose intron excision ratio 0 0 1.03
Adipose mRNA stability 0 0 0.96
BLA alternative polyA 0 0 0.97
BLA alternative TSS 0 0 0.96
BLA gene expression 0 0 1.02
BLA isoform ratio 0 0 1.06
BLA intron excision ratio 0 0 1.02
BLA mRNA stability 0 0 1.04
Brain alternative polyA 0 0 0.95
Brain alternative TSS 0 0 0.99
Brain gene expression 0 0 1
Brain isoform ratio 0 0 0.97
Brain intron excision ratio 0 0 1
Brain mRNA stability 0 0 0.99
Eye alternative polyA 0 0 1.18
Eye alternative TSS 0 0 1.05
Eye gene expression 0 0 1.07
Eye isoform ratio 0 0 1.12
Eye intron excision ratio 0 0 1.05
Eye mRNA stability 0 0 1.4
IL alternative polyA 0 0 1.05
IL alternative TSS 0 0 1.05
IL gene expression 0 0 0.99
IL isoform ratio 1 0.1 1.05
IL intron excision ratio 0 0 0.92
IL mRNA stability 0 0 0.99
LHb alternative polyA 0 0 1.1
LHb alternative TSS 0 0 1.19
LHb gene expression 0 0 0.98
LHb isoform ratio 0 0 0.99
LHb intron excision ratio 0 0 0.98
LHb mRNA stability 0 0 0.99
Liver alternative polyA 0 0 0.97
Liver alternative TSS 0 0 0.96
Liver gene expression 0 0 0.97
Liver isoform ratio 0 0 0.93
Liver intron excision ratio 0 0 0.99
Liver mRNA stability 0 0 0.99
NAcc alternative polyA 0 0 0.99
NAcc alternative TSS 0 0 1.03
NAcc gene expression 0 0 1.02
NAcc isoform ratio 0 0 1.01
NAcc intron excision ratio 0 0 0.97
NAcc mRNA stability 0 0 1.04
OFC alternative polyA 0 0 1.01
OFC alternative TSS 0 0 1.13
OFC gene expression 0 0 1
OFC isoform ratio 0 0 0.9
OFC intron excision ratio 0 0 0.92
OFC mRNA stability 0 0 1
PL alternative polyA 0 0 0.97
PL alternative TSS 0 0 1
PL gene expression 0 0 1
PL isoform ratio 1 0 1.04
PL intron excision ratio 0 0 0.98
PL mRNA stability 1 0 1.05