Hub : Genes

Tead1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XM_063267458.1 0.08 0.05 2.1e-07 0.05 0.05 0.04 0.04 1.4e-06 7.0e-06 3.9e-05 8.3e-06
2 Adipose isoform ratio NM_001198589.2 0.04 0.03 2.6e-04 0.02 0.02 0.01 0.01 2.7e-03 4.3e-03 1.7e-02 1.3e-02
3 NAcc isoform ratio XM_063267482.1 0.13 0.21 2.9e-03 0.02 0.01 0.02 0.02 5.0e-04 3.2e-03 8.2e-04 7.1e-04
4 Adipose alternative TSS XM_063267458.1 0.11 0.09 5.6e-08 0.05 0.05 0.04 0.05 3.0e-06 1.5e-06 1.4e-05 3.7e-06
5 Adipose alternative TSS XM_063267458.1 0.08 0.05 2.1e-07 0.05 0.05 0.04 0.04 6.9e-06 5.7e-06 2.0e-05 8.1e-06
6 Adipose alternative TSS XM_063267472.1 0.04 0.03 8.7e-05 0.03 0.03 0.03 0.03 3.6e-04 3.3e-04 6.4e-04 4.2e-04
7 Brain intron excision ratio chr1_176397762_176398545 0.04 0.03 2.1e-03 0.01 0.02 0.02 0.02 3.0e-02 5.9e-03 6.2e-03 7.1e-03
8 Liver mRNA stability Tead1 0.05 0.04 6.8e-04 0.01 0.01 0.01 0.01 1.2e-02 1.5e-02 3.0e-02 2.3e-02
9 Adipose alternative TSS XM_063267472.1 0.04 0.03 1.8e-04 0.03 0.03 0.02 0.03 3.2e-04 5.8e-04 1.3e-03 6.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.20.30.40.50.6-0.60.50.5-0.5-0.40.4-0.6
Area under the delay curve0.00.00.0-0.1-0.10.0-0.1-0.10.10.1-0.10.1
BMI with tail2.37.912.6-2.7-2.73.2-2.6-2.52.53.6-2.62.7
BMI without tail1.23.76.0-1.9-1.92.1-1.7-1.71.72.5-1.81.8
Body weight0.20.92.6-0.7-0.71.0-0.8-0.70.71.6-1.01.1
Weight adjusted by age0.30.50.9-0.5-0.50.6-0.9-0.91.0-0.3-0.70.7
Bone surface0.00.00.10.10.2-0.20.10.1-0.1-0.20.1-0.3
Bone volume0.10.10.2-0.3-0.20.3-0.3-0.30.40.3-0.50.2
Breakpoint value in progressive ratio session0.10.10.40.2-0.30.4-0.1-0.10.10.30.2-0.6
Number of licking bursts0.30.40.6-0.7-0.60.5-0.7-0.80.80.1-0.70.7
Context. condit. distance diff. score0.40.50.8-0.7-0.60.8-0.8-0.80.80.5-0.90.8
Locomotion velocity, session 11.01.01.2-1.1-1.11.1-1.0-1.01.00.9-1.00.9
Locomotion distance, session 14.45.57.1-2.4-2.42.7-2.4-2.42.42.0-2.32.3
Locomotion velocity, session 20.60.70.9-0.8-0.90.9-0.8-0.80.81.0-0.80.8
Locomotion distance, session 25.37.48.5-2.7-2.72.9-2.7-2.72.72.5-2.72.7
Locomotion velocity, session 30.00.00.1-0.2-0.20.2-0.2-0.20.2-0.2-0.10.2
Locomotion distance, session 30.10.10.40.20.3-0.10.20.1-0.1-0.60.2-0.1
Stereotopy head waving bouts, day 31.41.62.0-1.4-1.41.3-1.4-1.41.40.4-1.21.3
Stereotopy head waving duration, day 30.70.91.1-1.1-1.10.9-1.0-1.01.00.5-0.80.9
Locomotion velocity, session 70.00.10.10.30.3-0.00.20.2-0.20.30.1-0.1
Locomotion distance, session 70.30.40.60.70.8-0.50.70.7-0.7-0.40.6-0.7
Stereotopy head waving bouts, day 70.10.10.50.00.0-0.1-0.1-0.10.1-0.7-0.10.1
Stereotopy head waving duration, day 70.40.50.6-0.7-0.80.6-0.8-0.80.80.5-0.80.8
Locomotion velocity, session 80.40.40.6-0.6-0.70.7-0.7-0.70.8-0.2-0.60.6
Locomotion distance, session 83.34.95.6-2.2-2.12.4-2.2-2.22.31.9-2.32.2
Degree of sensitization distance0.50.60.9-0.7-0.70.7-0.7-0.70.71.0-0.80.7
Degree of sensitization stereotypy0.10.10.20.30.2-0.30.20.2-0.1-0.50.1-0.1
Conditioned locomotion0.40.40.50.60.7-0.50.70.7-0.7-0.30.7-0.7
Cocaine response after cond. corrected0.20.20.30.50.4-0.50.50.5-0.5-0.10.5-0.5
Cocaine response after cond. not corrected0.50.61.20.80.8-1.10.80.8-0.80.00.7-0.8
Cocaine response before conditioning0.10.20.50.40.3-0.70.30.4-0.40.40.1-0.3
Saline control response0.10.20.60.30.3-0.80.30.3-0.3-0.60.2-0.4
Bone: connectivity density0.20.30.50.60.6-0.50.60.6-0.6-0.10.5-0.7
Bone: cortical apparent density1.52.02.61.31.3-1.51.41.4-1.5-1.21.6-1.5
Bone: cortical area0.30.40.5-0.6-0.60.7-0.6-0.60.70.7-0.70.5
Bone: cortical porosity1.31.42.01.41.4-1.31.21.1-1.1-1.40.9-0.9
Bone: cortical porosity2.93.24.12.02.0-1.91.71.7-1.7-2.01.5-1.5
Bone: cortical thickness0.40.71.2-0.8-0.80.8-0.8-0.80.81.1-0.90.7
Bone: cortical thickness0.30.30.7-0.4-0.40.5-0.5-0.50.50.8-0.60.5
Bone: cortical tissue density1.52.12.71.31.3-1.51.51.5-1.5-1.21.7-1.5
Condit. Reinf. active minus inactive responses0.00.10.20.20.1-0.10.20.2-0.2-0.40.3-0.3
Condit. Reinf. active-inactive response ratio0.20.20.30.40.4-0.40.50.5-0.5-0.40.5-0.5
Condit. Reinf. active responses0.30.40.90.50.5-0.50.60.6-0.6-1.00.7-0.7
Condit. Reinf. inactive responses0.00.00.10.10.0-0.00.10.1-0.1-0.40.2-0.2
Incentive salience index mean1.01.21.51.11.0-1.01.11.1-1.2-0.71.2-1.2
Condit. Reinf. lever presses2.12.93.41.81.7-1.61.81.8-1.8-1.01.8-1.9
Condit. Reinf. active minus inactive responses1.31.72.0-1.4-1.31.4-1.4-1.41.40.4-1.31.4
Condit. Reinf. active-inactive response ratio0.20.20.3-0.5-0.40.5-0.5-0.50.50.1-0.40.5
Condit. Reinf. active responses1.11.61.9-1.4-1.31.3-1.3-1.41.40.5-1.21.4
Condit. Reinf. inactive responses0.20.30.3-0.6-0.60.4-0.6-0.60.50.3-0.50.6
Condit. Reinf. lever presses0.91.21.4-1.1-1.00.9-1.1-1.11.11.1-1.21.2
Condit. Reinf. lever reinforcers received0.71.01.2-1.1-1.01.0-1.1-1.11.10.2-1.01.1
Conditioned reinforcement - actives2.74.66.22.52.5-1.92.32.3-2.2-2.11.8-1.7
Conditioned reinforcement - inactives0.50.71.30.80.80.20.80.8-0.7-1.11.0-1.0
Conditioned locomotion4.45.76.82.62.6-1.72.52.5-2.4-2.52.5-2.2
Patch foraging indifference point 0 sec0.20.41.0-0.6-0.6-0.2-0.6-0.60.60.7-0.81.0
Patch foraging indifference point AUC0.50.81.7-0.8-0.81.3-0.9-0.90.90.5-0.80.8
Delay disc. indifference point, 0s delay0.10.10.3-0.1-0.1-0.2-0.3-0.30.3-0.6-0.10.1
Delay disc. indifference point, 16s delay0.20.20.30.50.5-0.40.40.4-0.4-0.50.5-0.4
Delay disc. indifference point, 2s delay0.10.10.20.20.2-0.40.20.2-0.2-0.40.2-0.2
Delay disc. indifference point, 24s delay1.01.21.51.11.1-0.81.21.2-1.2-0.61.1-1.1
Delay disc. indifference point, 4s delay0.40.50.7-0.7-0.70.4-0.8-0.90.90.1-0.70.7
Delay disc. indifference point, 8s delay1.01.11.5-1.1-1.11.1-1.0-1.01.01.2-1.11.1
Indifference point function ln k0.50.81.50.91.0-1.21.01.0-1.0-0.30.9-0.8
Indifference point function log k0.50.81.50.91.0-1.21.01.0-1.0-0.30.9-0.8
Patch foraging total patch changes 0 sec0.20.30.8-0.5-0.5-0.2-0.5-0.50.50.6-0.60.9
Patch foraging total patch changes 12 sec0.81.01.6-1.0-0.90.4-1.0-1.01.00.7-1.21.3
Patch foraging total patch changes 18 sec0.10.10.2-0.3-0.3-0.0-0.3-0.30.30.0-0.30.5
Patch foraging total patch changes 24 sec0.00.00.1-0.2-0.2-0.1-0.2-0.20.20.2-0.20.3
Patch foraging total patch changes 6 sec1.82.73.6-1.7-1.71.0-1.7-1.71.71.2-1.91.8
Patch foraging time to switch 0 sec0.20.31.20.50.5-1.10.50.5-0.5-0.50.4-0.4
Patch foraging water rate 0 sec0.20.50.60.70.7-0.70.80.8-0.8-0.50.8-0.6
Patch foraging water rate 12 sec1.12.34.7-1.4-1.41.6-1.4-1.41.42.2-1.51.4
Patch foraging water rate 18 sec0.20.31.3-0.5-0.50.4-0.4-0.30.31.2-0.30.2
Patch foraging water rate 24 sec1.82.54.6-1.6-1.51.8-1.4-1.41.42.2-1.41.3
Patch foraging water rate 6 sec1.31.92.51.41.4-1.01.51.5-1.5-0.91.6-1.5
Seeking ratio, delayed vs. immediate footshock0.30.30.50.50.5-0.10.70.7-0.7-0.00.7-0.7
Distance traveled before self-admin0.40.61.40.60.7-1.20.60.6-0.6-1.00.6-0.5
Distance traveled after self-admin0.91.12.50.81.1-1.61.01.0-1.1-0.91.0-0.7
Extensor digitorum longus weight0.31.35.1-1.0-1.01.0-0.9-0.90.82.3-0.80.9
Bone: elastic displacement0.10.10.1-0.2-0.20.2-0.3-0.30.30.1-0.40.4
Bone: elastic work0.60.70.9-0.8-0.80.9-0.9-0.90.90.8-0.90.8
Bone: endosteal estimation0.00.10.2-0.3-0.30.5-0.3-0.30.4-0.0-0.20.3
Bone: endosteal perimeter0.10.20.3-0.5-0.50.6-0.5-0.50.50.0-0.40.4
Epididymis fat weight0.31.22.8-0.9-0.91.1-0.9-0.90.91.7-1.01.1
Delta time in closed arm before/after self-admin0.10.10.2-0.1-0.20.5-0.3-0.30.30.3-0.50.3
Delta time in open arm before/after self-admin0.70.71.0-0.9-1.01.0-0.9-0.90.90.4-0.90.7
Diff in mean of infusions in LGA sessions0.00.10.20.2-0.2-0.3-0.0-0.00.0-0.40.1-0.4
Delay discount exponential model param0.00.00.00.20.2-0.00.10.1-0.1-0.20.2-0.2
Extinction: sum of active levers before priming0.20.20.20.50.4-0.20.50.4-0.4-0.40.4-0.5
Active lever presses in extinction session 60.10.10.40.30.1-0.10.20.2-0.2-0.20.4-0.6
Bone: final force0.00.00.1-0.1-0.10.1-0.1-0.20.2-0.4-0.20.0
Bone: final moment0.10.10.2-0.3-0.30.4-0.3-0.40.4-0.1-0.30.2
Food consumed during 24 hour testing period0.00.00.0-0.0-0.1-0.00.00.0-0.00.1-0.00.0
Glucose0.20.40.5-0.6-0.70.7-0.6-0.60.60.6-0.60.5
Heart weight1.72.62.9-1.7-1.61.5-1.7-1.71.71.3-1.61.7
Delay discount hyperbolic model param0.00.00.00.10.10.10.10.0-0.0-0.10.1-0.1
Intermittent access intake day 1-15 change0.00.10.60.20.20.80.10.1-0.10.20.1-0.0
Intermittent access intake escalation0.00.10.80.10.10.90.0-0.00.00.2-0.00.1
Intermittent access intake escalation 20.20.31.4-0.3-0.31.2-0.3-0.30.30.5-0.20.4
Intermitt. access day 1 inactive lever presses0.72.64.21.51.5-1.21.61.6-1.6-1.61.9-2.0
Intermitt. access day 15 inactive lever presses0.10.10.5-0.1-0.10.20.0-0.00.0-0.70.5-0.7
Intermitt. access escalation Index0.00.10.50.00.0-0.10.10.1-0.10.70.1-0.2
Intermittent access day 1 total infusions2.54.07.12.22.2-2.61.91.9-1.8-2.71.1-1.1
Intermittent access day 15 total infusions1.72.53.71.91.9-1.11.61.6-1.5-1.91.1-1.2
Intermittent access terminal intake (last 3 days)2.53.24.82.12.1-1.21.91.8-1.8-2.21.4-1.3
Intermittent access total infusions3.74.46.42.52.5-2.32.12.1-2.0-2.51.2-1.2
Intermittent access day 1 locomotion5.36.710.22.72.7-2.82.52.5-2.4-3.22.2-2.3
Intermittent access day 15 total locomotion3.66.57.52.72.7-2.02.62.6-2.5-2.62.5-2.6
Intermittent access total locomotion6.37.511.32.92.9-2.62.72.7-2.6-3.42.5-2.4
Intermittent access standard deviation0.61.23.3-0.6-0.61.1-0.9-1.01.00.3-1.61.8
Left kidney weight0.10.63.1-0.6-0.50.3-0.4-0.40.41.8-0.60.6
Right kidney weight0.20.83.7-0.8-0.80.6-0.6-0.60.51.9-0.70.7
Cocaine induced anxiety0.60.81.80.70.7-0.40.80.8-0.8-1.01.3-1.2
Post-drug Anxiety0.70.82.10.50.5-0.20.70.7-0.7-1.01.5-1.4
Baseline Anxiety0.30.30.4-0.6-0.60.5-0.6-0.60.60.6-0.60.4
Tail length0.62.53.51.61.6-1.91.51.5-1.5-1.81.3-1.5
Length with tail0.21.02.01.11.1-1.40.90.9-0.9-1.20.6-0.7
Length without tail0.20.71.11.01.0-0.90.80.8-0.7-1.00.5-0.5
Times rat made contact with spout0.10.10.1-0.3-0.3-0.0-0.3-0.30.30.0-0.30.3
Lifetime Intake3.03.65.22.32.3-2.11.91.9-1.8-2.31.0-1.0
Liver weight, left1.52.43.21.61.6-1.61.71.8-1.8-0.01.6-1.5
Liver weight, right1.12.02.61.51.5-1.31.51.6-1.6-0.31.5-1.5
Locomotor activity0.71.11.4-1.2-1.11.0-1.2-1.21.20.4-1.11.1
Locomotor testing distance1.32.43.0-1.7-1.71.4-1.7-1.71.70.6-1.51.5
Locomotor testing rearing3.06.17.4-2.6-2.62.5-2.7-2.72.71.0-2.42.4
Locomotion in novel chamber3.74.75.62.12.1-2.32.32.4-2.4-1.42.2-2.2
Locomotion in novel chamber post-restriction0.10.20.5-0.2-0.20.3-0.6-0.60.6-0.7-0.40.4
Fecal boli incidents, locomotor time 13.44.95.92.32.2-1.82.42.4-2.4-1.52.2-2.3
Change in fecal boli incidents, locomotor task5.35.26.0-2.3-2.32.2-2.4-2.42.51.7-2.32.3
Time >=10cm from walls, locomotor time 10.40.40.7-0.5-0.50.6-0.8-0.80.9-0.3-0.50.5
Bouts of movement, locomotor time 10.30.31.7-0.5-0.40.4-0.1-0.10.01.3-0.40.4
Total resting periods, locomotor time 10.10.10.70.00.1-0.10.40.4-0.40.80.1-0.1
Rest time, locomotor task time 10.10.10.2-0.3-0.30.4-0.4-0.50.5-0.2-0.30.3
Distance moved, locomotor task time 10.20.30.60.50.5-0.80.50.5-0.5-0.60.5-0.5
Vertical activity count, locomotor time 10.00.10.2-0.3-0.30.4-0.3-0.30.30.3-0.30.3
Time >=10cm from walls, locomotor time 21.62.33.6-1.5-1.51.9-1.5-1.51.51.3-1.51.5
Bouts of movement, locomotor time 20.10.20.60.50.5-0.40.40.3-0.3-0.80.5-0.5
Total resting periods, locomotor time 20.10.20.60.50.5-0.40.40.4-0.3-0.70.5-0.5
Rest time, locomotor task time 21.72.12.7-1.4-1.41.6-1.6-1.61.70.7-1.41.4
Distance moved, locomotor task time 20.10.10.20.20.2-0.40.30.3-0.30.00.2-0.2
Vertical activity count, locomotor time 20.10.20.2-0.4-0.40.4-0.4-0.40.40.4-0.40.4
Light reinforcement 10.41.11.5-1.0-1.01.0-1.1-1.11.00.8-1.01.2
Light reinforcement 20.30.42.3-0.5-0.50.3-0.4-0.40.31.5-0.50.6
Bone: marrow area0.00.10.1-0.2-0.30.4-0.3-0.30.3-0.1-0.20.2
Bone: maximum diameter0.30.50.6-0.8-0.80.8-0.8-0.80.80.4-0.80.7
Bone: maximum force0.30.40.6-0.7-0.60.7-0.7-0.70.80.2-0.80.6
Bone: maximum moment0.40.70.9-0.9-0.80.9-0.9-0.90.90.5-0.90.8
Mean time between licks in bursts0.30.81.10.90.8-1.00.90.9-1.0-0.80.9-0.9
Mean num. licks in bursts0.20.20.30.50.4-0.50.50.5-0.5-0.20.5-0.5
Cd content in liver1.82.03.11.41.4-1.41.41.4-1.4-1.81.4-1.3
Co content in liver0.70.81.10.70.8-1.00.90.9-0.9-1.00.9-0.9
Cu content in liver0.20.30.50.50.5-0.50.50.5-0.5-0.70.5-0.5
Fe content in liver1.21.51.91.31.3-1.31.31.3-1.3-0.21.3-1.4
K content in liver1.31.21.61.11.1-1.31.11.2-1.1-0.51.1-1.3
Mg content in liver0.20.20.30.40.4-0.60.50.5-0.50.30.5-0.6
Mn content in liver1.01.21.70.91.0-1.31.11.1-1.1-0.61.2-1.2
Na content in liver0.20.20.3-0.5-0.50.4-0.5-0.50.5-0.2-0.50.4
Rb content in liver2.22.54.61.41.5-1.61.51.5-1.5-2.11.5-1.6
Se content in liver2.52.93.41.71.8-1.81.71.7-1.7-1.61.6-1.8
Sr content in liver3.32.93.1-1.8-1.81.7-1.7-1.71.71.3-1.71.7
Zn content in liver0.70.81.5-0.8-0.80.8-0.9-0.80.81.2-0.80.9
Bone: minimum diameter0.40.60.8-0.8-0.80.9-0.8-0.80.80.8-0.70.8
Time in familiar zone, hab. session 11.71.61.9-1.2-1.21.4-1.2-1.21.21.3-1.31.2
Time in novel zone, hab. session 10.20.20.60.40.4-0.60.40.4-0.4-0.80.5-0.4
Total zone transitions, hab. session 12.43.35.0-1.8-1.82.2-1.9-2.02.00.8-1.81.7
Total locomotion distance, hab. session 10.81.11.6-1.0-1.01.3-1.1-1.11.10.5-1.11.0
Locomotion velocity, hab. session 10.81.21.7-1.0-1.01.3-1.1-1.11.20.6-1.21.1
Time in familiar zone, hab. session 20.30.40.5-0.6-0.70.7-0.6-0.60.60.5-0.50.6
Time in novel zone, hab. session 20.10.10.3-0.3-0.20.1-0.3-0.20.20.5-0.30.3
Total zone transitions, hab. session 23.34.25.1-2.0-2.02.3-2.1-2.12.11.6-2.12.1
Total locomotion distance, hab. session 22.53.33.8-1.7-1.71.9-1.8-1.81.81.6-1.91.9
Locomotion velocity, hab. session 22.23.03.5-1.7-1.61.8-1.8-1.81.81.4-1.91.8
Novel to familiar place preference ratio1.31.42.41.11.1-1.01.11.1-1.1-1.51.2-1.1
Novelty place preference0.80.92.00.90.9-0.80.90.8-0.8-1.41.0-0.9
Time in novel zone, NPP test0.50.51.50.70.7-0.50.60.6-0.6-1.20.8-0.7
Total zone transitions, NPP test2.33.34.2-1.8-1.82.1-1.8-1.81.81.8-1.81.8
Total locomotion distance, NPP test3.44.65.9-2.1-2.02.2-2.1-2.12.02.4-2.22.2
Locomotion velocity, NPP test3.04.35.7-2.0-2.02.2-2.0-2.02.02.4-2.12.1
Intraocular pressure0.00.00.1-0.2-0.20.2-0.2-0.20.2-0.1-0.10.2
Delta distance traveled before/after self-admin0.00.00.10.10.1-0.20.10.1-0.10.30.1-0.0
Delta ambulatory time before/after self-admin0.20.30.40.60.7-0.60.60.6-0.6-0.20.5-0.4
Parametrial fat weight0.10.20.30.50.5-0.40.50.6-0.60.10.6-0.5
Pavlov. Cond. lever latency3.13.94.9-2.0-1.91.8-2.1-2.12.11.1-2.12.2
Pavlov. Cond. magazine entry latency0.10.10.4-0.3-0.40.4-0.3-0.20.20.6-0.20.1
Pavlov. Cond. change in total contacts5.45.76.62.42.3-2.42.52.5-2.5-1.82.5-2.6
Pavlov. Cond. index score1.31.72.31.31.2-1.21.41.4-1.4-0.61.4-1.5
Pavlov. Cond. latency score1.72.22.91.51.4-1.31.61.6-1.6-0.81.6-1.7
Pavlov. Cond. lever contacts2.12.53.31.61.5-1.51.71.7-1.8-0.61.7-1.8
Pavlov. Cond. magazine entry number0.50.61.0-0.7-0.70.7-0.9-0.90.90.2-0.91.0
Pavlov. Cond. intertrial magazine entries0.10.10.80.30.3-0.10.20.2-0.2-0.90.3-0.3
Pavlov. Cond. lever-magazine prob. diff.1.51.92.61.31.3-1.31.51.5-1.5-0.81.5-1.6
Pavlov. Cond. response bias0.50.60.90.70.6-0.70.80.8-0.8-0.10.9-0.9
Pavlov. Cond. lever latency4.45.96.62.52.4-2.22.52.5-2.5-2.42.6-2.5
Pavlov. Cond. magazine entry latency1.31.53.4-1.2-1.20.8-1.2-1.11.11.8-1.31.2
Pavlov. Cond. change in total contacts5.48.69.5-3.0-3.02.9-3.1-3.13.12.1-3.13.0
Pavlov. Cond. index score3.85.15.9-2.3-2.21.9-2.3-2.22.22.4-2.42.3
Pavlov. Cond. latency score3.95.26.5-2.3-2.21.9-2.3-2.22.22.5-2.42.3
Pavlov. Cond. lever contacts3.75.15.7-2.3-2.22.1-2.3-2.32.32.3-2.42.3
Pavlov. Cond. magazine entry number3.24.04.42.02.0-1.72.02.0-2.0-2.02.1-2.0
Pavlov. Cond. intertrial magazine entries1.42.12.31.51.5-1.51.51.5-1.5-1.21.5-1.5
Pavlov. Cond. lever-magazine prob. diff.3.75.06.1-2.2-2.21.9-2.2-2.22.22.5-2.42.3
Pavlov. Cond. response bias3.95.35.8-2.3-2.32.1-2.3-2.32.32.2-2.42.3
Time in closed arm before self-admin1.31.73.0-1.6-1.20.5-1.3-1.31.21.1-1.31.7
Time in closed arm after self-admin0.10.10.3-0.4-0.2-0.4-0.3-0.20.20.6-0.30.5
Time in open arm before self-admin3.74.04.92.12.1-1.42.12.1-2.1-1.82.2-2.2
Time in open arm after self-admin0.10.10.6-0.2-0.30.8-0.1-0.20.2-0.10.0-0.1
Bone: periosteal estimation0.10.30.4-0.5-0.50.6-0.5-0.50.50.5-0.50.4
Bone: periosteal perimeter0.91.61.9-1.3-1.31.4-1.3-1.31.31.0-1.21.2
Bone: post-yield work0.40.61.0-0.8-0.81.0-0.8-0.80.80.2-0.70.8
Progressive ratio test 1 active lever presses2.02.43.91.81.8-1.51.61.5-1.5-2.01.2-1.0
Progressive ratio test 1 breakpoint1.82.23.71.71.7-1.51.51.5-1.4-1.91.1-0.9
Progressive ratio test 1 inactive lever presses0.10.10.30.50.5-0.20.30.3-0.3-0.50.0-0.0
Progressive ratio test 2 active lever presses4.55.37.12.62.6-2.72.32.3-2.3-2.51.7-1.5
Progressive ratio test 2 breakpoint4.75.47.32.62.6-2.72.32.3-2.3-2.51.7-1.5
Progressive ratio test 2 inactive lever presses2.33.75.82.22.2-1.61.91.9-1.8-2.41.6-1.5
Incentive Sensitization - Responses1.82.53.91.81.8-2.01.61.6-1.6-1.51.1-1.0
Incentive Sensitization - Breakpoint2.22.94.51.91.9-2.11.81.8-1.7-1.61.2-1.1
Sum of active levers in priming session hrs 5-60.10.10.3-0.3-0.50.5-0.3-0.30.30.3-0.1-0.1
Progressive ratio0.71.01.31.01.0-0.71.01.0-1.0-1.11.1-1.1
Food seeking constrained by brief footshock0.30.41.9-0.6-0.60.5-0.3-0.30.31.4-0.50.5
Seeking ratio, punishment vs. effort1.11.63.4-1.3-1.30.9-1.1-1.11.01.8-1.31.3
Retroperitoneal fat weight0.20.62.0-0.7-0.70.9-0.6-0.60.61.4-0.70.7
Reaction time number correct4.28.18.6-2.9-2.92.8-2.9-2.92.82.6-2.92.9
Reaction time mean minus median1.43.64.8-1.9-1.91.5-1.9-1.91.92.0-2.22.0
Reaction time mean minus median AUC1.53.75.0-1.8-1.81.7-1.9-1.81.82.2-2.22.0
Reaction time num false alarms2.73.84.31.91.9-2.02.02.0-2.0-1.52.1-2.0
Reaction time num false alarms AUC3.14.85.52.22.2-2.22.32.3-2.3-1.62.3-2.3
Reaction time trials correct on left4.28.18.6-2.9-2.92.8-2.9-2.92.82.6-2.92.9
Reaction time trials on left4.78.89.4-3.0-3.02.9-3.0-3.03.02.8-3.13.0
Reaction time mean0.00.10.1-0.2-0.3-0.2-0.3-0.30.3-0.2-0.40.3
Reaction time mean AUC0.00.00.30.00.0-0.40.0-0.00.0-0.5-0.10.0
Median of all reaction times0.20.20.70.30.3-0.80.30.3-0.3-0.80.3-0.4
Reaction time omissions3.75.46.0-2.4-2.32.3-2.3-2.32.32.2-2.42.2
Reaction time false alarm rate7.910.912.33.33.3-3.33.43.4-3.4-2.63.5-3.5
Reaction time premature initiation rate0.40.52.7-0.5-0.50.4-0.5-0.40.41.6-0.70.6
Reaction time premature initiations2.64.78.6-2.0-2.01.9-2.0-2.01.92.9-2.32.2
Std. dev. reaction times0.71.32.0-1.2-1.20.6-1.2-1.21.21.1-1.41.2
Reaction time trials completed4.78.89.4-3.0-3.02.9-3.0-3.03.02.8-3.13.0
Reaction time trials AUC4.38.18.7-2.9-2.92.8-2.9-2.92.82.6-2.92.9
Run reversals in cocaine runway, females0.10.10.6-0.0-0.0-0.10.20.2-0.30.8-0.10.2
Run reversals in cocaine runway, males1.61.62.41.21.2-1.51.31.3-1.3-1.11.2-1.2
Latency to leave start box in cocaine runway0.10.20.5-0.5-0.40.2-0.3-0.30.30.7-0.30.3
Latency to leave start box in cocaine runway, F0.00.00.1-0.00.1-0.20.20.3-0.30.30.2-0.3
Latency to leave start box in cocaine runway, M0.20.10.6-0.4-0.40.1-0.3-0.30.20.8-0.40.4
Std. dev. time between licks in bursts0.20.20.30.40.4-0.40.50.5-0.6-0.10.5-0.5
Total sessions with >9 infusions0.80.92.11.21.2-1.50.90.9-0.9-1.00.2-0.0
Short access day 1 total inactive lever presses0.50.70.90.70.7-0.90.80.7-0.8-0.90.8-1.0
Short access day 10 total inactive lever presses0.20.51.0-1.0-1.00.6-0.7-0.70.60.60.1-0.0
Short access day 1 total infusions1.92.54.21.81.8-2.01.61.6-1.6-1.41.1-1.0
Short access day 10 total infusions2.83.65.62.42.4-2.31.91.9-1.8-2.10.7-0.8
Short access total infusions2.43.15.32.12.1-2.31.81.8-1.7-1.80.8-0.9
Short access day 1 locomotion2.73.44.82.02.0-2.21.91.9-1.9-1.71.5-1.4
Short access day 10 total locomotion0.20.30.70.60.6-0.40.50.5-0.5-0.80.5-0.2
Short access total locomotion2.32.84.41.81.8-2.11.71.6-1.6-1.91.2-1.1
One hour access (0.3 mA shock)0.20.20.60.40.40.60.00.00.1-0.2-0.80.8
Compulsive drug intake1.51.83.4-1.5-1.51.5-1.3-1.31.21.8-0.80.7
One hour access (shock baseline)0.91.32.61.61.6-0.51.21.1-1.0-1.50.3-0.3
Social response proportion0.60.70.8-0.9-0.80.7-0.9-0.90.90.9-0.80.8
Social responses5.87.58.8-3.0-2.82.9-2.9-2.92.91.8-2.52.6
Social time3.64.86.0-2.4-2.32.2-2.4-2.42.41.0-2.22.1
Soleus weight0.00.10.50.10.2-0.20.10.2-0.20.70.0-0.2
Bone: stiffness0.20.21.10.40.4-0.40.40.3-0.3-1.00.3-0.5
Tibialis anterior weight0.41.33.7-0.9-1.01.0-1.0-0.90.91.9-1.01.0
Time to tail flick, vehicle, before self-admin0.00.00.10.20.0-0.10.00.0-0.0-0.30.0-0.2
Time to tail flick, vehicle, after self-admin0.50.71.2-1.1-0.90.8-0.9-0.90.90.3-0.70.9
Time to tail flick, test, before self-admin1.71.72.11.31.3-1.51.31.3-1.3-1.31.2-1.3
Time to tail flick, test, after self-admin0.60.61.00.80.7-0.90.80.7-0.7-1.00.7-0.8
Delta time to tail flick, vehicle, before/after SA0.70.61.1-1.0-0.80.7-0.8-0.80.80.6-0.71.0
Delta time to tail flick, test, before/after SA1.11.11.3-1.1-1.10.9-1.1-1.11.00.9-1.11.1
Tibia length0.82.32.81.51.5-1.41.61.6-1.6-1.01.7-1.7
Ambulatory time before self-admin0.91.42.81.01.1-1.71.11.1-1.1-1.41.1-1.0
Ambulatory time after self-admin2.52.95.31.61.8-2.31.71.7-1.7-1.61.5-1.3
Bone: tissue strength2.02.02.2-1.5-1.41.4-1.4-1.41.41.3-1.51.4
Total heroin consumption0.20.20.90.50.10.00.40.3-0.3-0.60.5-0.9
Bone: trabecular number0.10.10.30.30.4-0.30.30.3-0.3-0.50.3-0.5
Bone: trabecular spacing0.20.20.4-0.4-0.40.3-0.4-0.40.40.6-0.50.5
Bone: trabecular thickness0.40.50.7-0.7-0.70.8-0.8-0.80.80.3-0.80.8
Bone: trabecular tissue density0.30.41.60.50.4-0.50.50.4-0.4-1.30.6-0.6
Water consumed over 24 hours0.20.30.4-0.6-0.50.3-0.6-0.60.60.1-0.70.6
Number of responses in last shaping day4.24.66.12.52.5-2.42.22.2-2.1-2.41.5-1.3